摘要
用自制纯化牛硬脊膜内马尾神经根Ｐ２蛋白作为抗原，诱导家兔产生慢性复发性实验性变态反应性神经炎（ｃｒＥＡＮ），通过观察临床表现、电生理学、病理学改变，发现与人类慢性格林－巴利综合征（ｃＧＢＳ）相似。
Chronic relapsing experimental allergic neuritis (cr EAN) was induced in rabbits by the inoculation of purified P2 protein from bovine intradural nervi coccygeus rootIts clinical phenomenal observation and electrophysiological studies and histological studies similarities with human chronic GullainBarre syndrome (cGBS)It is suggested that the pathogenesis of cGBS and crEAN are due to an autoimmune reaction related with P2 protein
出处
《免疫学杂志》
CAS
CSCD
北大核心
1998年第1期28-31,共4页
Immunological Journal
关键词
P2蛋白
慢性
G-B综合征
病因
动物模型
P2 protein,Chronic GuillianBarre syndrome, Chronic relapsing experimental allergic neuritis, Animal model
