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羟基脲生殖毒性的研究进展 被引量：3

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作者 韩宁 杨建一 李莉
机构地区 山西医科大学细胞生物与遗传学教研室
出处 《中国优生与遗传杂志》 2008年第12期5-6,共2页 Chinese Journal of Birth Health & Heredity
基金 山西医科大学基础医学院"学科研究方向建设基金"(20040708)
关键词 羟基脲 生殖毒性 血-脑脊液屏障 血药浓度 分子式 内代谢
分类号 R363 [医药卫生—病理学]
  • 相关文献

参考文献20

  • 1Michael Lee, Jung Kwon, Se Nyun Kim. cDNA microarray gene expression profiling of hydroxyurea, paclitaxel, and panisidine, genotoxic compounds with differing tumorigenicity results [ J ]. Environmental and Molecular Mutagenesisi, 2003,42 ( 2 ) : 91 - 97.
  • 2陈瑶.β-地中海贫血药物基因治疗研究进展[J].中国优生与遗传杂志,2003,11(2):123-124. 被引量：2
  • 3Lisziewicz J, Foli A, Lori WM, et al. Hydroxyurea in the treatment of HIV,infection : clinical efficacy and safety concerns [ J ]. Drug Sa, 2003,26(9) : 605 -624.
  • 4Fattori A, de Souza RA, Saad ST. Acute myocardial infarction in sickle cell disease: a possible complication of hydroxyurea treatment [ J ]. Hematol J,2005,5 (7) : 589 - 590.
  • 5Randi ML,et al. Toxicity and side effects of hydroxyurea used for primary thrombocythemia [ J ]. Platelets ,2005,16 ( 3 - 4 ) : 181 - 184.
  • 6Lee M,et al. cDNA microarray gene expression profiling of hydroxyurea, paclitaxel ,and p -anisidine,genotoxiccompounds with differing tumorigenicity resuhs[J]. Environ Mol Mutagen,2003,42:91 -97.
  • 7Sakano K, Oikawa S, Hasegawa K, et al. Hydroxyurea induces site - specific DNA damage via formation of Hydrogen peroxide and nitric oxide[J]. Jpn J Cancer Res,2001,92( 11 ) : 1166 - 1174.
  • 8Andersson M, et al. Extended - term cultures of human T - lymphocytes and the comet assay: a useful combination when testing for genotoxicity in vitro [ J ]. Matat Res ,2003 ,540 ( 1 ) : 43 - 55.
  • 9周莉,吴纯启,廖明阳.羟基脲对大鼠胚胎中脑细胞增殖和分化的影响[J].癌变·畸变·突变,2007,19(1):22-25. 被引量：3
  • 10Gye Hyeong Wooa, Kei - ichi Katayama, et al. Effects of prenatal hydroxyurea- treatment on mouse offspring [ J ]. Experimental and Toxicologic Pathology ,2004,56 : 1 - 7.

二级参考文献16

  • 1周莉,吴纯启,廖明阳.羟基脲对雄性大鼠的生殖毒性[J].中国临床药理学与治疗学,2005,10(12):1330-1334. 被引量：6
  • 2李勇,戴修道.啮齿类动物肢芽和中脑细胞培养技术在致畸研究中的应用[J].中国公共卫生,1997,13(3):185-186. 被引量：3
  • 3Chahoud I, Kuriyama SN, Paumgartten FJ. Maternal protein-and-energy restriction reducesthe developmental toxicity of cyclophosphamide and hydroxyurea in rats. Toxicology, 2002,179: 137-149.
  • 4Oakley OR, Hughes NK, Phillips JD, et al. The effects of lithium in reversing hydroxyurea induced suppression of hematopoietic progenitor cells in vitro using retroviral infected long-term marrow cultures. Rom J Physiol, 1998,35:67-78.
  • 5Lisziewicz J, Foli A, Lori WM. Hydroxyurea in the treatment of HIV infection:clinical efficacy and safety concerns. Drug Saf,2003,26 : 605-624.
  • 6Evenson DP, Jost LK. Hydroxyurea exposure alters mouse testicular kinetics and sperm chromatin structure. Cell Prolif,1993,26: 147-159.
  • 7Wiger R, Hongslo JK, Evenson DP, et al. Effects of acetaminophen and hydroxyurea on spermatogenesis and sperm chromatin structure in laboratory mice. Reprod Toxicol, 1995,9:21-33.
  • 8Ferguson RP,Anm A, Carter C, et al. Hydroxyurea treatment of sickle cell anemia in hospital-based practices[J] . Am J Hematol, 2002, 70(4): 326-328.
  • 9Lisziewicz J, Foli A, Loff WM. Hydroxyurea in the treatment of HIV infection: clinical efficacy and safety concerns[J] Drug Safe, 2003, 26 (9):605-624.
  • 10Flint OP.A micromass culture method for rat embryonic neural cells[J]. J Cell Sci, 1983,61:247-262.

共引文献8

同被引文献40

引证文献3

二级引证文献10

中国优生与遗传杂志
2008年 第12期

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