摘要
目的探讨舒血宁注射液对急性心肌梗死非血运重建患者内皮素、P选择素的影响。方法将70例急性心肌梗死非血运重建患者随机分为治疗组(舒血宁注射液+常规药物治疗)、对照组(常规药物治疗),观察两组患者治疗14d后血浆内皮素、P选择素的变化。结果舒血宁注射液治疗组血浆内皮素、P选择素水平降低,与对照组比较差异有统计学意义(P<0.05)。结论舒血宁注射液对急性心肌梗死患者有改善血管内皮功能障碍、抗血小板活化的作用。
Objective To explore the impact of Shuxuening injection to endothelin and P-selectin of acute myocardial infarction in patients with non-revascularization. Methods 70 cases of acute myocardial infarction in patients with non-revascularization were randomly divided into treatment group (Shuxuening injection + conventional drug therapy), the control group ( conventional drug therapy), patients were observed for the change of plasma endothelin, P-selectin level after 14 days. Results The plasma endothelin and P-seleetin levels decrease in the treatment group with Shuxuening injection, compared with the control group there were significant differences ( P 〈 0. 05 ). Conclusion For the patients with acute myocardial infarction, Shuxuening injection can improve their vascular endothelial dysfunction, and make the role of anti-platelet activation.
出处
《中国实用医药》
2009年第1期44-45,共2页
China Practical Medicine
关键词
舒血宁注射液
急性心肌梗死
内皮素
P选择素
Shuxuening injection
Acute myocardial infarction
Endothelin
P-selectin