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舒血宁注射液对急性心肌梗死非血运重建患者内皮素、P选择素的影响 被引量:20

The impact of Shuxuening injection to endothelin and P-selectin of acute myocardial infarction in patients with non-revascularization
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摘要 目的探讨舒血宁注射液对急性心肌梗死非血运重建患者内皮素、P选择素的影响。方法将70例急性心肌梗死非血运重建患者随机分为治疗组(舒血宁注射液+常规药物治疗)、对照组(常规药物治疗),观察两组患者治疗14d后血浆内皮素、P选择素的变化。结果舒血宁注射液治疗组血浆内皮素、P选择素水平降低,与对照组比较差异有统计学意义(P<0.05)。结论舒血宁注射液对急性心肌梗死患者有改善血管内皮功能障碍、抗血小板活化的作用。 Objective To explore the impact of Shuxuening injection to endothelin and P-selectin of acute myocardial infarction in patients with non-revascularization. Methods 70 cases of acute myocardial infarction in patients with non-revascularization were randomly divided into treatment group (Shuxuening injection + conventional drug therapy), the control group ( conventional drug therapy), patients were observed for the change of plasma endothelin, P-selectin level after 14 days. Results The plasma endothelin and P-seleetin levels decrease in the treatment group with Shuxuening injection, compared with the control group there were significant differences ( P 〈 0. 05 ). Conclusion For the patients with acute myocardial infarction, Shuxuening injection can improve their vascular endothelial dysfunction, and make the role of anti-platelet activation.
作者 江春晓
出处 《中国实用医药》 2009年第1期44-45,共2页 China Practical Medicine
关键词 舒血宁注射液 急性心肌梗死 内皮素 P选择素 Shuxuening injection Acute myocardial infarction Endothelin P-selectin
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参考文献3

  • 1Yanagisawa M,Kurihara H,Kimura S,et al.A novel potent vasoconstrictor peptide produced by vascular endothelial cells[].Nature.1988
  • 2Berger R,Pacher,R.The role of the endothelin system in myocardial infarction-new therapeutic tarqets[].European Heart Journal.2003
  • 3Wagner,D.D.New links between inflammation and thrombosis[].Arteriosclerosis and Thrombosis.2005

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