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应用基因芯片技术研究大鼠妊娠期胰岛基因表达谱的变化

Application of microarray technique in gene expression analysis of pancreatic islets in pregnant rats
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摘要 利用基因芯片技术研究大鼠妊娠不同阶段胰岛基因表达谱的变化。与正常对照组相比，大鼠妊娠期数百条基因发生差异表达，其中基因Reg3α在孕期表达显著高于正常对照组，可能与胰岛再生相关。 Genechip was applied to explore gene expression profile of islets in rats at various stages of pregnancy. Compared with the normal control group, differential expressions of hundreds of genes were detected during pregnancy. Reg3α gene expression was markedly increased during pregnancy, which may be related to islet regeneration.
作者 薛莹 刘翠萍 袁庆新 徐宽枫 徐瑜 茅晓东 陈国芳 刘超
机构地区 南京医科大学第一附属医院内分泌科
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2008年第6期658-659,共2页 Chinese Journal of Endocrinology and Metabolism
关键词 妊娠 基因表达 寡核苷酸序列分析 胰岛再生 Pregnancy Gene expression Oligonucleotide array sequence analysis Islet regeneration
分类号 R587.1 [医药卫生—内分泌]
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参考文献5

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二级参考文献15

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中华内分泌代谢杂志
2008年 第6期

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