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阿托伐他汀联合卡维地洛治疗冠心病慢性心力衰竭疗效观察 被引量:2

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摘要 目的观察阿托伐他汀联合卡维地洛对冠心病慢性心力衰竭的影响。方法2004年8月至2006年8月门诊及住院的冠心病慢性心力衰竭患者95例。所有患者随机分为3组,3组均接受利尿剂、硝酸酯类药物、ACEI类及地高辛常规治疗,有急性心力衰竭的在急性心力衰竭控制后分组治疗。卡维地洛组在常规治疗基础上加用卡维地洛;阿托伐他汀组在常规治疗基础上加阿托伐他汀;联合治疗组在常规治疗基础上加用上述2种药物。所有患者检查TC、LDL-C、C-反应蛋白(CRP)、左室射血分数(LVEF)。治疗2个月后复查。对所有患者2年来的资料进行总结分析,统计患者住院次数、住院总日数及病死率。结果各组与治疗前相比较,TC、LDL-C、CRP均有不同程度降低,LVEF则有明显提高;联合治疗组治疗2个月后TC、LDL-C、CRP显著低于卡维地洛组(P<0.05)。联合治疗组LVEF显著高于阿托伐他汀组和卡维地洛组,差异有显著性(P<0.05);住院次数、住院总日数、病死率均降低,但差异无显著性。结论阿托伐他汀联合卡维地洛治疗冠心病慢性心力衰竭能够明显改善患者预后。
出处 《中国厂矿医学》 2008年第6期664-665,共2页 Chinese Medicine of Factory and Mine
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