摘要
采集北京市丰台区城区和4个乡镇家养犬血清样品1 299份,采用免疫荧光中和试验法检测血清狂犬病病毒抗体效价。结果显示,被调查犬中有59.7%接种过狂犬疫苗,城区和乡镇接种率分别为75.9%和30.1%;有32.1%未接种过狂犬疫苗,城区和乡镇分别占16.1%和61.4%;有8.2%不清楚是否接种过狂犬疫苗,城区和乡镇分别占8%和8.5%。免疫犬狂犬病中和抗体效价d 0.5的占疫苗接种犬的57.1%,城区和乡镇分别为60.7%和40.6%。未免疫犬狂犬病中和抗体效价d>0的占未接种疫苗犬的27.6%,城区和乡镇分别为42.6%和20.3%。106只免疫不详犬均有狂犬病中和抗体。本次调查发现,犬群中仅有39%的犬只具有有效的狂犬病保护性抗体,疫苗接种率和狂犬病毒抗体效价城区均好于乡镇,但总体免疫水平仍不能有效控制群体中狂犬病的爆发和流行。
To investigate the rabies antigen and antibody prevalence among domesticated dogs in Beijing Fengtai district. 1 299 serum samples were collected from the Fengtai city and four countries and the rabies antibodies were measured. The results showed that dogs injected rabies vaccine in the whole dogs were 59.7%. The inoculation rate were 75.9 % in the city,and 30.1% in the counties. And dogs uninjected rabies vaccine were 32.1%. The inoculation rate were 16.1% in the city,and 61.4% is in the counties. 8.2% of 1 299 dogs were unknown about the injectiom of rabies vaccine. Among the dogs injected rabies vaccine,the protective level （d≥0.5 international units （IU/mL） of the rabies virus antibody were 57.1%. It were 60.7 % in the city,and 40.6 % is in the countries. But among the dogs uninjected rabies vaccine,the rabies antibody （d〉0 were is 27.6%. It were 42.6% in the city,and 20.3% is in the countries. The survey suggested that the inoculation rate of the rabies vaccine and the protected seroprevalence of the rabies virus antibody in the city is higher than those in the countries,and the protected seroprevalence of rabies virus antibody is too low to protect and control the rabies.
出处
《中国兽医学报》
CAS
CSCD
北大核心
2008年第12期1404-1406,1410,共4页
Chinese Journal of Veterinary Science
基金
北京市科委应用基础研究与战略高技术主题项目(D07080200720701)
关键词
犬
狂犬病
抗体效价
流行病学调查
dog
rabies
valence of antibody
serum epidemiology
