摘要
目的观察奥硝唑、定君生合并用药治疗细菌性阴道病(BV)的疗效。方法:将门诊150名BV患者随机分为三组(n=50):A组口服奥硝唑6天,B组阴道用乳酸杆菌活菌胶囊10天,C组口服奥硝唑6d,随后用乳酸杆菌活菌胶囊10d,评定疗效。结果A、B、C三组治愈率分别为70.00%、60.00%、78.00%,有效率分别为88.00%、82.00%、97.00%,C组有效率明显高于B组(P<0.05);2个月内复发率三组分别是14.00%、6.00%和0,C组明显低于A组,差异显著(P<0.05);不良反应率分别是10.00%、0.00%、8.00%,三组间无显著性差异,(P>0.05)。结论奥硝唑合并乳酸杆菌活菌胶囊治疗BV疗效高,不良反应发生率低。
Objectives To observe the curative effect of Ornidazole （ONZ） and dingjunsheng for bacterial vaginosis （BV）. Methods 150 patients with BV in outpatient department of gynecology were randomly dev- ided into 3 groups：Group A were treated with oral Ornidazole 0.5, bid ×6two times every day , six days; Group B were treated with living preparation oflactobacillus （dingjunsheng） by vaginal administration; Group C were treated with both oral Ornidazole and vaginal administration of alive Lactobacillus capsules. Results The cure rate of 3 groups was 70.00%, 60.00%, 78.00% respectively. The effective ratio of them was 为 88.00% , 82.00% ,97.00% respectively. The effective ratio of group C was significantly higher than that of group B（P 〈 0.05 ） ;The relapse rate was 14.00% ,6.00% ,0. The rate in group C was significant lower than that in group A （P 〈 0.05） ;The rate of adverse effect in 3 groups was 10.00%, 0.00%, 8.00% respectively （ P 〉 0.05 ）. Conclusion With lower relapse rate and adverse effective rate, the ONZ combined with living preparation of Lactobacillus（dingjunsheng） can cure BV most effectively.
出处
《中国实用医药》
2008年第32期38-39,共2页
China Practical Medicine
关键词
奥硝唑
定君生
细菌性阴道病(BV)
Ornidazole
DingjunshengDingjunsheng
Bacterial Bacterial vaginosis
