摘要
本文研究了工业碳黑有机溶剂萃取物的致突变性.发现其萃取物在Ames试验中显示极强的直接致突变性,特别是经过硝化工艺的碳黑.而且萃取溶剂不同,其致突变性也不同,以氯苯和二氯甲烷为溶剂的萃取物活性较高.经进一步分析测定,在萃取物中含有二硝基芘和3-硝基芴酮等硝基多环芳烃,前者是一种非常强的直接致突变物,它们是工业碳黑致突变性的主要供献者,光照可以降低碳黑萃取物的致突变活性.
Mutagcnicity of extracts of carbon black was studied. Extracts by organic Solvents were found distinctly positive in Ames test. Data indicated that the muta-genicity of extracts of nitrifed carbon black is two quantity grades higher than that of original carbon black.Diffeient organic solvents were used for extraction. The extracts with chlorobenzene and dichloromethane showed the highest muta-genicity.Nitro-PAHs, especially dinitropyrencs, are the main direct mutagcnS in nitrifed carbon black.After photo-exposure, both extracts of carbon black and nitro-PAH standards showed reduction in mutagenicity.
出处
《环境化学》
CAS
CSCD
北大核心
1990年第3期51-54,共4页
Environmental Chemistry
基金
国家自然科学基金
