摘要
目的探讨小儿轮状病毒性肠炎心肌损害各项指标的变化。方法将59例大便轮状病毒抗原阳性患儿空腹抽血查肌钙蛋白Ⅰ(cTnⅠ)、肌酸激酶同工酶(CK-MB),阳性者30例,与抽血同一天做心电图、心脏彩超。同时抽取健康对照组18例,做相同的检查。结果cTnI、CK-MB 2组差异有统计学意义,心脏彩超EF、FS、E/A、LAD/ASD 2组差异无统计学意义;心电图研究组较对照组变化明显。结论小儿轮状病毒性肠炎可有不同程度的心肌损害。多数临床表现轻微,以潜伏型和临床亚型为主,cTnl、CK-MB较灵敏、特异。
[ Objective] To investigate the changes of various index of myocardial injury caused by rotavirus enteritis in children. [ Methods] Fifty nine children whose stool rotavirus antigens were positive were phlebotomized to detect serum levels of cTnI and CK MB in limosis condition. Thirty children who showed positive result were checked by electrocardiogram ( ECG) and multicolor uhra- sonic cardiogram at the same time. Eighteen children were sampled as healthy control group with the same examinations. [ Results] There were significant differences in serum levels of cTnI and CK MB between two groups. The difference in EF, FS, E/A and LAD/ASD between two groups was not significant. The change in ECG of study group was more obvious than that of control group. [ Conclusion] The different levels of myocardial injury were induced by rotavirus enteritis in children. The majority patient was deli- tescent type or sub-clinical type, and had slight clinical symptoms. The detection of cTnI and CK MB is specific and sensitive.
出处
《职业与健康》
CAS
2008年第24期2752-2753,共2页
Occupation and Health