摘要
本文报告2例卡氏肺囊虫性肺炎。临床上主要表现为发热、咳嗽和抗生素治疗无效。X线和CT检查示肺部点片状阴影。病理组织学特点是间质性肺炎、肺泡或支气管内泡沫状物质沉积，六胺银染色在泡沫状物质中查见圆形或半月形，直径6～8μm的卡氏肺囊虫虫体。本病是由卡氏肺囊虫感染引起的一种特殊的间质性肺炎，常见于营养不良和免疫功能低下者，尤其是AIDS患者。确诊靠病原体检查，包括痰和组织标本的Giernsa染色、TBO染色、PAS染色、GMS染色、免疫组化和PCR。据此可与肺泡蛋白沉积症、粟粒性肺结核、军团菌性肺炎、霉菌性肺炎、细支气管肺泡癌、特发性肺间质纤维化等鉴别。
Two cases of pneumocystis carinii pneumonia (PCP) were reported clinicopathologically. Both of themshowed pyrexia, cough and no effects to antibiotic treatment. The roentgenography and computerized tomographyrevealed point and massive lesions of lung. Pathohistological features were as follows: interstitial pneumonia,frothy materials in lung alveoli and bronchi. Pneumocystis carinii were identified by Groccot rnethenamine silverstain in the frothy materials, which were round or semilunar bodies with diarneter of 6-8 μm. PCP is a special interstitial pneumonia caused by pneumocystis carinii which of ten infects persons with malnutrition or hypoirnmunity, especially, the patients with AIDS. Its correct diagnosls is based on causative agent detection of sputum andhistospecimens, including Giemsa stain, toluidine blue stain, methenamine silver stain, immunohistochemical stainand polymerase chain reaction. Differential diagnosis can be made by the methods mentioned above from alveolarproteinosis, miliary lung tuberculosis, legionnairs pneumonia, fungal pneumonia, bronchio - alveolar carcinoma,as well as idiopathic interstitial fibrosis of the lung.
出处
《诊断病理学杂志》
CSCD
1997年第2期80-82,共3页
Chinese Journal of Diagnostic Pathology
关键词
卡氏肺囊虫
间质性肺炎
临床病理
诊断
Pneumocystis carinii Interstitial pneumonia Clinicopathology Diagnosis
