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血浆同型半胱氨酸与颈动脉狭窄严重程度及中医证型的关系 被引量:2

Degree and Relation of Syndromes Types of Traditional Chinese Medicine between Plasma Homocysteine and Casrotid Stegnosis
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摘要 目的:探讨血浆同型半胱氨酸与颈动脉狭窄及中医证型的关系。方法:将69例入选的患者按颈动脉狭窄程度及中医辨证分型分别分组,采用循环酶法测定患者血浆同型半胱氨酸(Hcy)水平,并对各组Hcy进行比较。结果:重度颈动脉狭窄患者Hcy水平明显高于中度颈动脉狭窄患者(P<0.05),中度颈动脉狭窄患者高于轻度颈动脉狭窄患者(P<0.05),且三者均明显高于对照组(P<0.05);肝阳上扰型患者Hcy水平低于痰浊中阻和气血亏虚型(均P<0.05)。结论:血浆Hcy的异常增高是颈动脉狭窄的一个危险因素,也是气血亏虚证和痰浊中阻证的主要血液理化特征之一。 Objective:To explore the degree and relation of TCM syndromes types of traditional Chinese medicine between plasma homocysteine and casrotid stegnosis.Methods:69 casrotid stegnosis patients were selected and classified into different groups by the degree of casrotid stegnosis and the types of TCM syndromes.A circulation enzyme method was used to determine the level of the plasma homocysteine(Hcy) of the patients and the comparison was made among the groups.Results:The level of Hcy of the severe patients was obviously higher than that of the moderate patients(P<0.05) while the level of the moderate patients was higher than that of the slight patients(P<0.05).The three groups were obviously higher than that of the control group(P<0.05).The Hcy level of liver-yang type patients was lower than that of the phlegm stagnation and qi-deficiency syndrome patients(P<0.05).Conclusion:The abnormal increase of the plasma Hcy level is a risky factor of casrotid stegnosis and also a physicochemical characteristic of qi and blood deficiency and phlegm stagnation syndrome.
出处 《云南中医中药杂志》 2008年第11期4-6,共3页 Yunnan Journal of Traditional Chinese Medicine and Materia Medica
关键词 颈动脉狭窄 血浆同型半胱氨酸 辨证分型 casrotid stegnosis plasma homocysteine differentiation classification of syndrome
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  • 1Li Z, Sun L, Zhang H, et al. Elevated plasma homoeysteine was associated with hemorrhagic and isehemic stroke, but methylenetetrahydrofolate reductase gene C677T polymor-phism was a risk factor for thrombotic stroke: a multieenter ease control study in ehina[J]. Stroke, 2003,34 (9):2085.
  • 2李保华,毛利忠,王克义,雷志锴,牛国忠.脑梗死与高同型半胱氨酸血症的相关性研究[J].中国实用神经疾病杂志,2006,9(1):8-10. 被引量:97
  • 3North American Symptomatic Carotid Endartereetomy Trial Collaboration. Beneficial effect of carotid endarterectomy in symptomatic patients with high grade carotid stenosis [J]. N Engt J Med. 1991 : 325-453.
  • 4Clarke R, Daly L, Robinson K, et al. Hyperhomocys-einemia: an independent risk factor for vascular disease. N Engl Med[J]. 1991, 324-1155.
  • 5Graham IM, Daly LE, Refsum HM, et al. Plasma homo-cysteine as a risk factor for vascular disease[J]. JAMA, 1997,277-1781.
  • 6Chen C,Conklin BS,Ren Z,et al. Homocysteine decreases endotheliurn-dependent vasore laxation in porcine arteries[J]. J Surg Res, 2002,102(1):22-30.
  • 7李毅敏,张连凤,宋宏良,王金良,马丽鹃,胡宗华.血浆同型半胱氨酸的检测和与缺血性心脑血管疾病的关系[J].天津医药,2003,31(11):724-726. 被引量:7
  • 8李保华,陶云海,王克义,牛国忠.脑梗死患者血浆同型半胱氨酸检测的临床意义[J].浙江临床医学,2006,8(1):17-18. 被引量:22
  • 9Jander S, Sitzer M, Wendt A, et al. Expression of tissue factor in high-grade carotid artery stenosis, association with plaque destabilization [J]. Stroke, 2001,32 (4) : 850-854.
  • 10孔丽君.冠心病患者血浆同型半胱氨酸水平与辨证分型相关性研究[J].实用中西医结合临床,2004,4(1):7-8. 被引量:44

二级参考文献33

  • 1第一届全国内科学术会议心血管病组.关于冠状动脉性心脏病命名及诊断标准的建议[J].中华心血管病杂志,1981,9(1):75-76.
  • 2Boushey CJ,Beresford SA,Omenn GS,et al.A quantitative assessment of plasma homocysteine as a risk factor for vascular disease.JAMA,1995,274:1049-1057.
  • 3Lalouschek W,Aull S,Serles W,et al.Genetic and nongenetic factors influencing plasma homocysteine levels in patients with ischemic cerebrovascular disease and healthy control subjects.J Lab Clin Med,1999,133:575-582.
  • 4McCully KS.Vascular pathology of homocysteinemia:implications for the pathgenesis of atherosclerosis.Am J Pathol,1969,56:111-128.
  • 5Brattstrom L,Lindgren A,Israelsson B,et al.Hyperhomocysteinemia in stroke:prevalence cause and relationships to type of stroke and stroke risk factors.Eur Clin Invest,1992,22:214-221.
  • 6Boysen G,Brander T,Christensen H,et al.Homocysteine and risk of recurrent stroke.Stroke,2003,34(5):1258-1261.
  • 7Martinelli I,Battaglioli T,Pedotti P,et al.Hyperhomocysteine in cerebral vein thrombosis.Blood,2003,102(4):1363-1366.
  • 8Lentz SR.Mechanisms of thrombosis in hyperhomocysteinemia.Curr Opin Hematol,1998,5(5):343-349.
  • 9[1]Boushey CJ,Beresford SA,Omenn GS,et al.A quantitative assessment of plasma homocysteine as a risk factor for vascular disease[J].JAMA,1995,274:1049~1057
  • 10[2]Lalouschek W,Aull S,Serles W,et al.Genetic and nongenetic factors influencing plasma homocysteine levels in patients with ischemic cerebrovascular disease and healthy control subjects[J].J Lab Clin Med,1999,133:575~582

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