摘要
目的探讨超声引导下经皮微波凝固治疗(PMCT)复发性肝癌的疗效和可行性。方法50例复发性肝癌患者在超声引导下行PMCT,根据肿瘤大小选择不同微波功率和作用时间。术后1个月观察肿瘤的大小、内部血流变化和并发症。结果治疗1个月后超声检查显示肿块出现不同程度的缩小,其内部回声增强;彩色多普勒及能量多普勒检查均显示肿瘤内血流减少或消失,其中36例(72%)患者肿瘤完全凝固坏死;12例(24%)患者原发病灶有局部残留,直接接受第2次PMCT,术后均完全凝固;2例(4%)患者肝内其他部位出现新病灶改行其它治疗。未发现严重并发症和不良反应。术后随访3-12个月,4例患者原治疗肿瘤周边出现新的复发灶,其余未见复发。结论就近期疗效看,超声引导下微波凝固治疗适用于复发性肝癌患者的治疗;其远期疗效有待于病例数的进一步增加与随访时间的延长。
Objective To evaluate the feasibility and effect of ultrasound-guided percutaneous microwave coagulation therapy for intrahepatie recurrecnt cancer of primary hepatocelluar carcinoma. Methods Fifty patients with recurrent liver cancer were treated with ultrasound-guided percutaneous microwave coagulation therapy. The different microwave export power and time were selected according to tumor size. The change of the tumor size, blood flow and the associated complications were observed after a month. Results After a month treatment all nodules dwindled in size. The internal echo strengthened color tratumuoral blood flow signals decreased or disappeared the tumor nodules of 72 % were coagulative necrosis totally. Twelve patients (24 %) still had lesion. After second sourery the lesion disappeared, 2 patients 4 % showed new lesion in livers and treatmented by other way. There were no serious complications or side effect in all patients. Follow-up after 3-12 months,only 4 cases of patients with the treatment of the original tumor recurrence peripheral the emergence of new recurrence of lesions and the rest no recurrence. Conclusion As far as the short-term curative effect,the percutaneous microwave coagulation therapy for liver cancers is safe and effective. It is suitable to treat intrahepatic recurrent cancer. To evaluate long-term curative effect, we should increase the number of patients and prolong the visit time.
出处
《江西医学院学报》
CAS
2008年第5期60-62,F0004,共4页
Acta Academiae Medicinae Jiangxi
关键词
复发性肝癌
经皮微波凝固治疗
超声引导
recurrent hepatocarcinoma
percutaneous microwave coagulation therapy
ultrasound-guided