摘要
目的研究部分理化因子对肠道病毒的灭活效果,为预防和控制肠道病毒性传染病传播流行选择合理有效的方法。方法采用悬液定量和载体定量试验法对热力、紫外线和部分化学消毒剂灭活脊髓灰质炎病毒的效果进行了观察。结果在恒温水浴器中加热60℃作用5 m in,对悬液内脊髓灰质炎病毒灭活对数值达到4.0以上;经辐照强度为120μW/cm2紫外线作用5 m in,对玻片上脊髓灰质炎病毒的灭活对数值达4.00以上。用含有效碘1500mg/L碘伏消毒液作用30 m in,对悬液内脊髓灰质炎病毒灭活对数值达到4.0以上;四种胍类消毒剂、季铵盐水溶液和体积分数75%乙醇对悬液内脊髓灰质炎病毒灭活对数值均小于4.00。结论普通湿热、紫外线和碘伏消毒液均可有效灭活脊髓灰质炎病毒,季铵盐类和胍类消毒剂水溶液不能灭活脊髓灰质炎病毒。
Objective To study the efficacy of some physical and chemical agents in inactivating enterovirus in order to choose reasonable and effective method for prevention and control of prevalence of infectious disease caused by enterovirns. Methods Suspension and carrier quantitative tests were used to observe the efficacy of heat, ultraviolet rays and some chemical disinfectants in inactivating poliovirus. Results After exposure to 60℃ for 5 rain or ultraviolet irradiation at intensity of 120μ W/cm^2 for 5 rain, the reduction factors （ log10 ） of poliovirns attained higher than 4.00. The reduction factor （ log10 ） of poliovirus in suspension exposed to iodophor disinfection solution containing available iodine 1500 mg/L for 30 min attained over 4.00. The reduction factors （ log10 ） of poliovirus in suspension exposed to four guanidine disinfectants, quaternary ammonium salt solution or 75% ethanol could not attain 4.00. Conclusions Heat, ultraviolet rays and iodophor disinfection solution have good efficacy in inactivating poliovirus, while guanidine disinfectants, quaternary ammonium salt solution and 75% ethanol can not inactivate poliovirns effectively.
出处
《中国消毒学杂志》
CAS
北大核心
2008年第6期587-589,共3页
Chinese Journal of Disinfection
关键词
脊髓灰质炎病毒
热力
紫外线
化学消毒剂
灭活效果
polioviru
heat
ultraviolet rays
chemical disinfectants
inactivating efficacy
