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酶联免疫斑点技术及其在结核分枝杆菌感染诊断中的研究进展 被引量：1

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摘要 结核病已经成为一个严重的公共卫生问题，我国已有1／3人口感染了结核菌，受感染人数超过了4亿，据研究受感染人口中有10％的人发生结核病。因此，提高早期诊断结核病和结核潜伏感染（1atent tuberculosis infection，LTBI）的水平对于结核病的控制具有极为重要的价值。结核病的诊断主要依靠影像学检查、结核菌素试验（tuberculin skin test，TST）及痰结核菌培养等方法。TST应用的抗原缺乏特异性，
作者 刘菲 张宗德
机构地区 北京市结核病胸部肿瘤研究所结核病分子生物学研究室
出处 《中华检验医学杂志》 CAS CSCD 北大核心 2008年第11期1310-1312,共3页 Chinese Journal of Laboratory Medicine
关键词 结核分枝杆菌 感染诊断 酶联免疫斑点技术 TUBERCULOSIS 结核菌素试验 公共卫生问题 痰结核菌培养 结核病
分类号 R686 [医药卫生—骨科学]
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参考文献18

  • 1李婧,王怀明,张建业.分枝杆菌的分子生物学诊断[J].国外医学（临床生物化学与检验学分册）,2002,23(4):204-205. 被引量：7
  • 2陈茶,黄彬,姜傥.一种细胞免疫学新技术——酶联免疫斑点技术[J].国际检验医学杂志,2006,27(3):243-246. 被引量：7
  • 3侯世芳,许贤豪,刘广志,乔立艳,矫毓娟,张华,国红,文诗广,殷剑,魏雪飞,刘江红,王红.酶联免疫斑点(ELISPOT)技术的应用(讲座)[J].中国神经免疫学和神经病学杂志,2002,9(4):200-202. 被引量：19
  • 4Czerkinsky CC, Nilsson LA, Nygren H, et al. A solid-phase enzyme-linked immunospot (ELISPOT) assay for enumeration of specific antibody-secreting cells. J lmmunol Methods, 1983,65: 109-121.
  • 5张辉,潘志明,焦新安.一种细胞因子检测新方法——ELISPOT技术[J].动物医学进展,2004,25(6):29-31. 被引量：8
  • 6Cole ST, Brosch R, Parkhill J, et al. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature, 1998, 393 : 537-544.
  • 7Lalvani A, Pathan AA, Mcshane H, et al. Rapid detection of Mycobacterium tuberculosis infection by enumeration of antigen- specific T cell. Am J Respir Crit Care Med,2001,163: 824-828.
  • 8Lalvani A, Nagvenkar P, Udvadia Z, et al. Enumeration of cells specific for RDl-encoded antigen suggests a high prevelance of latent Mycobacterium tuberculosis infection in healthy urban India. J Infect Dis, 2001,183:469-477.
  • 9Hill PC, Sillah DJ, Fox A, et al. ESAT45/CFP-10 fusion protein and peptides for optimal diagnosis of Mycobacterium tuberculosis infection by ex vivo enzyme-linked immunospot assay in the Gambia. J Clin Microbiol,2005,43: 2070-2074.
  • 10Lawn SD, Bangani N, Vogt M, et al. Utility of Interferon-gamma ELISPOT assay responses in highly tuberculosis-exposed patients with advanced HIV infection in South Africa. BMC Infect Dis, 2007,7:99.

二级参考文献48

  • 1廖爱华,VERA RebmannHANS,Grosse-Wilde.ELISpot:一种新的检测人类HLA-Ⅰ抗体的方法[J].中国免疫学杂志,2005,21(1):52-55. 被引量：1
  • 2Van der Meide P H, Joosten A M, Hermans P, et al. Assessment of the inhibitory effect of immunosuppressive agents on rat of T cell interferon-γ production using an ELISPOT assay[J]. Immunol Metheds, 1991,144:203-205.
  • 3Herr W, Linn B, Leister N, et al. The use of computer-assisted video image analysis for the quantification of CD8+ T lymphocytes producing tumor necrosis factor alpha spots in response to peptide antigens[J]. Immunol Methods, 1997,203(2):141-152.
  • 4Chitnis Vivek, Pahwa R, Pahwa S. Determinants of HIV-Specific CD8 T-cell responses in HIV-infected pediatric patients and enhancement of HIV-gag-specific responses with exogenous IL-15[J]. Clinical Immunology, 2003,107:36-45.1[14] Atanackovic D, Matsuo M,
  • 5Bagley K C, Shata M T, Onyabe D Y, et al. Immunogenicity of DNA vaccines that direct the coincident expression of the 120 kDa glycoprotein of human immunodeficiency virus and the catalytic domain of cholera toxin[J]. Vaccine, 2003,21:3335-3341.
  • 6Bastos R G, Dellagostin O A, Barletta R G , et al. Immune response of pigs inoculated with Mycobacterium bovis BCG expressing a truncated form of GP5 and M protein of porcine reproductive and respiratory syndrome virus[J]. Vaccine, 2004,22:467-474.
  • 7Li W, Watarai S, Iwasaki T, et al. Suppression of Salmonella enterica serovar Enteritidis excretion by intraocular vaccination with fimbriae proteins incorporated in liposomes[J].Developmental and Comparative Immunology, 2004,28:29-38.
  • 8Okamoto Y, Gotoh Y, Shiraishi H, et al. A human dual-color enzyme-linked immunospot assay for simultaneous detection of interleukin 2- and interleukin 4-secreting cells[J]. International Immunopharmacology, 2004,(4):149-156.
  • 9Van der Meide P H,De Labie M C, Ruuls S R, et al. Discontinuation of treatment with IFN-beta leads to exacerbation of experimental autoimmune encephalomyelitis in Lewis rats Rapid reversal of the antiproliferative activity of IFN-beta and excessive expans
  • 10Kamm C, koberne M, Geginat G, et al. CD8 T cell immunome analysis of Listeria monocytogenes[J]. FEMS Immunology and Medical Microbiology, 2003,35:235-242.

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中华检验医学杂志
2008年 第11期

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