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精神分裂症患者一级亲属人格特征的研究 被引量:8

Personality traits in individuals at high risk for schizophrenia
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摘要 目的探讨精神分裂症患者一级亲属的人格特征。方法采用分裂型人格问卷(SPQ)及三维人格问卷(TPQ)评定181例精神分裂症患者一级亲属(高危组)、321名正常对照个体(对照组)的人格特征。结果高危组SPQ阴性分裂型人格维度评分[(9.80±7.05)分]高于对照组[(8.42±5.87)分],差异有统计学意义(P〈0.05)。高危组在TPQ寻求新奇维度评分[(15.60±5.62)分]、奖赏依赖维度评分[(17.41±1.13)分]与对照组[(14.20±2.83)分,(18.22±3.26)分]的差异均有统计学意义(P均〈0.01)。高危组的阴性分裂型人格维度分数与寻求新奇维度、奖赏依赖维度分数显著相关(r=0.17和-0.23)。结论精神分裂症患者一级亲属具有阴性分裂型维度、寻求新奇维度、奖赏依赖维度的人格特征。 Objective To explore the personality traits in individuals at high risk for schizophrenia. Methods All 181 individuals at high risk for schizophrenia whose parents or siblings were affected with schizophrenia, and 321 normal controls were assessed with the Sehizotypal Personality Questionnaire (SPQ) and Tridimensional Personality Questionnaire (TPQ). Results The score of negative schizotypal dimension of SPQ was higher in the individuals at high risk than controls ( P 〈 0. 05 ). The novelty-seeking dimension and reward-dependence dimension of TPQ were significant lower in the individuals at high risk for schizophrenia than controls ( P 〈 0. 01 ). The score of negative schizotypal dimension was related to the scores of novelty-seeking dimension and reward-dependence dimension of TPQ ( r = 0. 17 and - 0. 23 ). Conclusion The individuals at high risk for schizophrenia have some personality traits such as negative schizotypal dimension in SPQ, noveltyseeking dimension and reward-dependence dimension in TPQ.
出处 《中华精神科杂志》 CAS CSCD 北大核心 2008年第4期193-195,共3页 Chinese Journal of Psychiatry
基金 国家自然科学基金杰出青年基金资助项目(30125014)
关键词 精神分裂症 家庭关系 疾病遗传易感性 人格 Schizophrenia Family relations Genetic predisposition to disease Personality
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参考文献11

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