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遗传性心律失常分子生物学与临床研究进展

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摘要 猝死是当今人类死亡的重要原因之一。在猝死复杂的病因中，心源性猝死（sudden cardiac death，SCD）占猝死的80％。在青少年人群中发生的猝死，遗传性心律失常是常见原因。分子生物学及基因组学等研究进展，对心律失常基因机制有了长足的认识，基因的突变在遗传性长QT综合征、短QT综合征、Brugada综合征和儿茶酚胺依赖性多形性室性心动过速被证实，并可预测年轻人猝死的危险性，因而，心律失常基因机制研究成为近年来心血管领域内的一个研究前沿。以下分别对与猝死有关的遗传性心律失常的分子生物学与临床研究进展作一综述。
作者 许子彬 许炳灿 黄至斌
机构地区 中山大学附属第二医院急诊科
出处 《中国急救复苏与灾害医学杂志》 2008年第11期694-698,共5页 China Journal of Emergency Resuscitation and Disaster Medicine
关键词 遗传性心律失常 分子生物学 临床研究 BRUGADA综合征 遗传性长QT综合征 多形性室性心动过速 心源性猝死 短QT综合征
分类号 R541.7 [医药卫生—心血管疾病] R373.21 [医药卫生—病原生物学]
  • 相关文献

参考文献33

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二级参考文献14

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共引文献7

中国急救复苏与灾害医学杂志
2008年 第11期

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