摘要
目的观察血必净注射液对严重脓毒症患者呼吸机相关性肺炎发生的影响。方法严重脓毒症并发呼吸衰竭需要机械通气的成年住院患者100名,随机分为血必净治疗组和常规对照组,观察两组病人呼吸机相关性肺炎的发生率,28天病死率,ICU住院时间,呼吸机治疗时间以及抗生素使用天数。结果血必净治疗组呼吸机相关性肺炎的发生率,病死率降低,ICU住院时间,呼吸机治疗时间以及抗生素使用天数缩短,有统计学差异。结论血必净可以降低严重脓毒症患者发生呼吸机相关性肺炎的发病率。
Objective To observe the influence of of Xuebijing injection on the morbidity of ventilator-associated pneumonia in patients with severe sepsis. Methods 100 patients with severe sepsis were randomly divided into 2 groups： control group and Xuebijing group. The morbidity of ventilator-associated pneumonia,28-day mortality, the number of the days in ICU, days weaning from mechanical ventilation, and of days of acquired antibiotics were observed as the outcome measures. Results The morbidity of ventilator-associated pneumonia and the 28-day in the xuebijing group were significantly reduced, the number of days in ICU, weaning from mechanical ventilation and acquired antibiotics were also significantly reduced. Conclusion The therapy with Xuebijing injection may decrease the morbidity of ventilator-associated pneumonia in patients with severe sepsis.
出处
《临床肺科杂志》
2008年第12期1552-1553,共2页
Journal of Clinical Pulmonary Medicine
