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败血症的研究进展 被引量:5

Recent Research And Development of Sepsis
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摘要 败血症(sepsis)是一高发病率高死亡率的综合征,目前还没有行之有效的特效治疗,成为当今医学领域的一大挑战。对其病理过程、动物模型、治疗方法的充分认识有利于进一步的研究,为新的突破性的治疗方法提供一个新的思路,本文就相关方面作一综述。 Sepsis is a syndrom with a high incidence rate and mortality. To date there's no effective therapy to save the lives of patients with sepsis and therefore it becomes a great challege of the medical field. Thus, the knowledgement of pathological process, animal models and therapeutic methods will faliciate the further research and provide a novel strategy for the treatment of sepsis. Here we review on these contents.
作者 蔡金莲
出处 《中山大学研究生学刊(自然科学与医学版)》 2008年第3期1-7,共7页 Journal of the Graduates Sun YAT-SEN University(Natural Sciences.Medicine)
关键词 败血症 病理过程 动物模型 细胞因子 治疗 Sepsis, pathological process, animal models, cytokine, therapy
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参考文献10

  • 1Buras,J.A.,B.Holzmann,,M.Sitkovsky.Animal models of sepsis:setting the stage[].Nature Reviews Drug Discovery.2005
  • 2Blackwell,T.S.,J.W.Christman.Sepsis and cytokines:current status[].British Journal of Anaesthesia.1996
  • 3Fischer,E.et al.Interleukin-1receptor blockade improves survival and hemodynamic perform-ance in Escherichia coli septic shock,but fails to alter host responses to sublethal endotoxemia[].The Journal of Clinical Investigation.1992
  • 4Diao,H.,M.Kohanawa.Endogenous interleukin-6plays a crucial protective role in strepto-coccal toxic shock syndrome via suppression of tumor necrosis factor alpha production[].Infection and Immunity.2005
  • 5Pastores,S.M.Drotrecogin alfa(activated):a novel therapeutic strategy for severe sepsis[].Postgraduate Medical Journal.2003
  • 6Otero,R.M.et al.Early goal-directed therapy in severe sepsis and septic shock revisited:con-cepts,controversies,and contemporary findings[].Chest.2006
  • 7Reuben,A.D.et al.Early goal-directed therapy:a UK perspective[].Emergency Medicine Journal.2006
  • 8.Severe sepsis and the role of novel therapeutic agents.Position statement of the Critical Care Society of South Africa on severe sepsis and the role of novel therapeutic agents such as drotrecogin alfa(ac-tivated)[].South African Medical Journal.2003
  • 9Teti,G.,G.Mancuso,F.Tomasello.Cytokine appearance and effects of anti-tumor necro-sis factor alpha antibodies in a neonatal rat model of group B streptococcal infection[].Infection and Immunity.1993
  • 10Kerschen,E.J.et al.Endotoxemia and sepsis mortality reduction by non-anticoagulant activa-ted protein C[].The Journal of Experimental Medicine.2007

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