摘要
目的:探讨护肝药在结核病治疗中应用的价值。方法:研究我院2007~2008年上半年期间住院治疗150例肺结核患者应用护肝药的情况,比较在采取相同抗痨方案基础上应用及未应用护肝药的患者出现肝功能损害的情况,并比较应用护肝药与未应用护肝药而出现肝功能损害的效价比。选用STATA8.0统计软件,采用Spearman相关分析。结果:应用护肝药的结核病患者出现肝功能损害明显低于未应用护肝药的患者。应用护肝药的结核病患者的花费稍高于未应用患者,但有较高的获益率。结论:结核病患者在常规抗痨的同时应用护肝药可以从中获益。
OBJECTIVE: To discuss the application value of liver aid in the treatment of tuberculosis. METHODS: The use of liver aid drugs in 150 patients with pulmonary tuberculosis (TB) hospitalized in our hospital between 2007 and the first half year of 2008 was studied and the lesion of liver function in patients receiving antiphthisic treatment alone or in combination with liver aid was compared. STATA8.0 statistics software was used for Spearman correlation analysis. RESULTS: The incidence of lesion of liver function in patients receving antiphthisic treatment plus aid liver was signficantly lower than in those receiving no liver aid. The cost in those receiving liver aid was a lit bit higher than in those without receiving liver aid, but the benefit rate in the former was higher. CONCLUSION: TB patients can benefit from the concomitant use of liver aid during routine antiphthisic treatment.
出处
《中国医院用药评价与分析》
2008年第10期782-783,共2页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
护肝药
肝毒性
结核病
获益率
Liver aid
Hepatotoxicity
Tuberculosis
Benefit rate