摘要
目的探讨促排卵周期前应用妈富隆对体外受精-胚胎移植(IVF-ET)中卵巢反应不良者的价值。方法将52例行IVF的卵巢反应不良患者按排卵周期前是否使用妈富隆分为研究组24例和对照组28例。结果研究组促性腺激素平均用量(39.24±4.57支)较对照组(42.56±5.97支)少,受精率、优质胚胎数高于对照组(P<0.05)。但两组获卵数、周期取消率、临床妊娠率差异无统计学意义。结论对卵巢反应不良的患者,在实施IVF-ET前口服妈富隆可改善促排卵治疗结局,提高受精率及优质胚胎数目。
Objective To study the effects of Maivelow administered before the stimulation cycle on poor responder patients undergoing in vitro fertilization-embryo transfer（IVF-ET） cycles.Methods 52 poor responder patients undergoing IVF-ET cycles were divided into 2 groups according to the history whether the patients had been treated with Maivelow before the ovulatory period（research group,n=24） or not treated with the drug（control group,n=28）.A statistical analysis of the anamnestic data of the patients was carried out for the assessment of the ovulation-promoting effect of Maivelow and their influence on the IVF-ET operation.ResultsThe required dosis of gonadotrophin was lower in patients pre-treated with Maivelow than that in patients of the control group.The fertilization rate and number of good embryo more than the control group（P〈0.05）.The differences between patients of the two groups with respect to number of oocyte retrieval,the cycle cancel rate and clinical pregnancy rate were not significant.Conclusion Maivelow administered before IVF-ET can improve the effects of ovulation-promotive treatment,increase the fertilization rate and number of good embryo in poor responder patients.
出处
《宁夏医学杂志》
CAS
2008年第10期892-893,共2页
Ningxia Medical Journal
关键词
妈富隆
体外受精-胚胎移植
卵巢低反应
Maivelow
In vitro fertilization-embryo transfer
Poor responder
