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补肾益肝方对卵巢切除所致大鼠骨质疏松症的治疗作用 被引量:4

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摘要 目的:探讨补肾益肝方对骨质疏松症的治疗作用。方法:以卵巢切除所致的骨质疏松大鼠为动物模型,采用骨组织形态计量学方法测定胫骨TBV%、TRS%、TFS%、MAR、OWS和mAR。结果:大鼠切除卵巢后,胫骨TBV%显著降低,TRS%以及TFS%、MAR、OWS和mAR均显著增高,从而表明卵巢切除所造成的是一种骨吸收大于骨形成的高转换型骨质疏松症。给大鼠灌服补肾益肝方后,能使上述情况发生逆转,即能使TBV%显著增高,使TRS%以及TFS%、MAR、OWS和mAR均显著降低。结论:补肾益肝方对骨质疏松症具有良好的治疗作用。
出处 《中国中医基础医学杂志》 CAS CSCD 北大核心 2008年第9期696-697,共2页 JOURNAL OF BASIC CHINESE MEDICINE
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