摘要
研究了光诱导自由基链式亲核取代（ＳＲＮ１）反应生成的Ｎ－（α－萘基）苯并咪唑、Ｎ－（β－萘基）苯并咪唑和Ｎ－（α－吡啶基）苯并咪唑的薄层光密度定量方法，并成功地应用于其反应机理的研究。该法简便、快速、准确。线性范围０～３０μｇ，平均回收率９９８％～１００５％，相对标准偏差＜４７％。
A thin layer chromatographic(TLC)densitometric method for the determination of N (α naphthyl)benzimidazole,N (β naphthyl)benzimidazole and N (α pyridyl)benzimidazole is described The method has been successfully applied to the study of photo induced S RN 1 reaction mechanism and products The reaction products were separated on a silica gel plate with a mixed solvent of cyclohexane and ethyl acetate (1+1),and scanned by a TLC scanner with a reflection mode The method is simple,rapid and accurate,with a linear range 0～3 0 μg for all three substituted benzimidazoles The relative standard deviations are< 4 7%,while the recoveries are 99 8%～100 5%
出处
《分析测试学报》
CAS
CSCD
1997年第5期8-10,共3页
Journal of Instrumental Analysis
基金
山西省重点学科基金
关键词
α-萘基
苯并咪唑
β-萘基
α-吡啶基
薄层色谱
N (α Naphthyl)benzimidazole,N (β Naphthyl)benzimidazole, N (α Pyridyl)benzimidazole,S RN 1 reaction,TLC densitometry
