摘要
用3H－TdR掺入法，测定受分次γ线照射的小鼠脾淋巴细胞转化功能，同时测定受照小鼠胞、肺、肝、脾SOD活力和LPO含量。结果表明，榄香烯提高了小鼠T、B淋巴细胞的辐射抗性（P＜0．05），以及脾、肝、肺SOD活力（p＜0．01、P＜0．05），降低脾LPO含量（p＜0．01）。提示榄香烯的辐射免疫保护机理之一，是由于增强组织SOD活力，降低LPO含量，从而减少自由基及有害物质对淋巴细胞的损伤。
The transformation of spleen lymphocytes after fractionated γ-irradiation was studied by method of 3H-Tdr incorporation, and the SOD activity and LPO content in brain, lung, liver and apleen were measured, and the effects of elemene on immunity and oxidative damage were investigated. The results indilated that elemene could enhance radiation resistance of T.B lymphocyts (P< 0 .05), increase SOD activity in spleen, lung and liver (P < 0. 01 and P < 0. 05 ) and decrease LPO content in spleen (P < 0.01 ). The formation of mechanism of protection may be due to scavenging free radical and relieveing damage of lymphocyts.
出处
《苏州医学院学报》
1997年第5期814-815,共2页
Acta Academiae Medicinae Suzhou
