摘要
目的探讨男性乳腺癌的临床特点、治疗及预后。方法回顾性分析30例男性乳腺癌患者的临床资料,采用Kaplan-Meier法计算生存率。结果本组5年总生存率为67%。Ⅰ期患者5年生存率为100%,Ⅱ期患者5年生存率为60%,Ⅲ期患者5年生存率为43%,Ⅳ期患者无5年生存病例。单因素分析示肿瘤大小(P=0.006)、腋窝淋巴结转移情况(P=0.013)和肿瘤分期(P=0.004)影响患者预后。Cox回归多因素分析示肿瘤分期(P=0.009)是影响预后的主要因素。结论以手术为主的综合治疗是男性乳腺癌的治疗模式,其预后与肿瘤分期有关。
Objective To evaluate the clinical characteristics, therapeutic methods and prognosis of male breast cancer cases. Methods The clinical data of 30 patients diagnosed with male breast cancer were analyzed retrospectively. The survival rate was calculated hy Kaplan-Meier. Results The 5-year overall survival rate was 67% in the group. The 5-year survival rate was 100% for stage Ⅰ breast cancer, 60% for stage Ⅱ , and 43% for stage Ⅲ, but no cases of stage Ⅳsurvived for 5 years. It was found by single-variant analysis that the tumor size （ P = 0. 006 ）, axillary lymph node status （ P = 0.013 ） and tumor stage （ P = 0. 004 ） significantly influenced the outcome of the patients~ Multi-variant Cox regressiofi showed that tumor stage （P = 0. 009 ） was an independent factor. Conclusion The male breast cancer is an uncommon disease. It has a lower incidence rate, older age of onset and poor prognosis. Infiltrating ductal carcinoma is the main pathological type. Operation-based combined therapy may improve the outcome of the male breast cancer patients and will be a standard care for these patients. Tumor staging is an independent prognostic factor.
出处
《中华乳腺病杂志（电子版）》
CAS
2008年第5期18-21,共4页
Chinese Journal of Breast Disease(Electronic Edition)
关键词
男性乳腺癌
治疗
预后
Male breast cancer
Treatment
Prognosis
