摘要
目的探讨三种给药方案治疗细菌性阴道病的临床疗效、安全性和费用。方法采用随机对照研究,选择细菌性阴道病患者180例,保妇康栓组、奥硝唑泡腾片组、克林霉素磷酸酯阴道片组各60例,每天分别阴道各置入保妇康栓、奥硝唑泡腾片、克林霉素磷酸酯阴道片1枚,疗程7d,于停药后3-5d观察疗效、安全性,并运用药物经济学方法进行分析。结果停药后3-5d,保妇康栓组、奥哨唑泡腾片组、克林霉素磷酸酯阴道片组的治疗有效率分别为88.5%、94.1%和86.5%,三组间比较,差异无显著性(p>0.05),保妇康栓组成本最低且疗效好。结论保妇康栓是治疗细菌性阴道病的安全有效药物,且成本低,副作用小,值得临床推广。
Objective To estimate the efficacy, safety and cost- effectiveness of four administration in the treatment of bacterial vaginosis. Methods 180 patients with bacterial vaginosis were randomly divided into 3 groups, every group (n=60) was treated with Baofukang suppository, ornidazole vaginal effervescent tablet, clin- damycin phosphate suppository respectively. Seven successive days were taken as a course for three groups. The efficacy and safety were accessed respectively 3- 5d after end of treatment. Results The efficacy rates were 88.5% in Baofukang suppository group, 94.1% in ornidazole vaginal effervescent tablet group and 86.5% in clindamycin phosphate suppository group respectively 3- 5d after end of treatment. There was no significant dif- ference in clinical efficacy between three groups(P>0.05). The cost of Baofukang suppository with good efficiency is the lowest. Conclusion Baofukang is effective, safe and lowest in the treatment of bacterial vaginosis.
出处
《海南医学》
CAS
2008年第10期143-144,共2页
Hainan Medical Journal
关键词
细菌性阴道病
药物治疗
药物经济学分析
Bacterial vaginosis
Administration
Pharmaceutical economic analysis
