摘要
本文收集了１９８０～１９９０年滋养细胞肿瘤１８０例，其中侵饰性葡萄胎（恶葡）１１８例，绒毛膜癌（绒癌）６２例。治疗方法：采用化疗为主的综合治疗方案，首选药物为５－氟脲嘧啶（５－ＦＵ）和更生霉素（ＫＳＭ），８天或５天为一疗程，间隔时间分别为３周或２周。结果：恶葡的生存率为９８．３％；绒癌的生存率为８５．４％；总的死亡率为１４．５２％。结论：５天一疗程的化疗效果相似于８天的疗程效果，而且化疗副反应轻，周期间隔短，病人易于接受，故临床应推广；同时对于某些病例尚须手术治疗。
This article collected 180 trophoblastic tumor cases treated in our hospital from 1980 to 1990.Invasion Hydatidiform Mole(IHM) 118;Choriocarcinoma(CC) 62.Treatment method is combined therapy based chemotherapy.5FU and KSM are the first choice.One course of treatment is eight days or five,which is implemented at intervals of three weeks or two respectively.Results:The surviral rate of IHM and CC is 98.3% and 85.4% respectively;The death rate of CC is 1452%.Conclusions:The chemotherapy effects of five days course is the same with that of eight days.Its sideeffects is lighter and course interval is shorter.This way should be recommended.In the mean time operation should be performed to some cases.
关键词
滋养细胞肿瘤
葡萄胎
绒毛膜癌
化学疗法
Trophoblastic Tumor Invasive Hydatidiform Mole Choriocarcinoma Chemotherapy.
