摘要
本文报道了近10年鼻咽癌放射治疗后出现眼部损伤13例（14只眼），其中鼻咽癌Ⅱ期7例，Ⅲ期6例．放射性白内障3例（4只眼），视网膜病变5例．视神经病变4例，合并白内障1例．发病时间为单程放疗后3年-6年，再程放疗后2年4个月-3年9个月．经临床及CT检查均排除鼻咽癌的复发和转移．发病原因均系由射线直接引起晶状体囊下上皮细胞损伤和放射性血管损伤所致，与放射野的设置、总放射量、分割剂量、存活时间、肿瘤的复发、个人身体状况等多种因素有关．我们认为预防和减少本病的发生，根据临床具体情况，周密制定放疗方案，对随访复查病人眼部检查应列为常规项目．同时对发病机理，眼部表现，治疗方法等进行了简单的讨论．
It was reported that optic lesion of 13 patients with NPC were resulted by irradiation (14eyes). II-stage of NPC patients accounted for 7 cases, III-stage 6 cases. In this series, the irradiationinduced cataract accounted for 3 cases (4 eyes), optic retina injury 5 cases, optic nerve damage 4 cases,of which 1 case with cataract. The optic lesion occured from 3 years to 6 years after first radiation course,2 years and 4 months to 3 years and 9 months after second course. It was eliminated recurrence ormetastasis by chinical cell and nutritious blood vessel of lens capsule. It was associated with the multiplefactors of treatment part, total dose, frectionation dose, suvival period, recurrence and physical state. Forprevention and descending the injury we should accurately formulate the therapeutic plan according tothe patients' actual conditions. Ophthalmic examination should be as a routine program for the follow-uppatients. We discussed simply to the pathogenic principle, optic expression and therapeutic method et al.
出处
《伤残医学杂志》
1997年第4期37-40,共4页
Medical Journal of Trauma and Disability
关键词
鼻咽癌
放射疗法
眼部损伤
鼻咽肿瘤
Nasopharyngeal cancer (NPC) Radiotherapy Optic lesion
