摘要
目的探讨老年2型糖尿病(T2DM)患者血清胆红素水平与颈动脉粥样硬化程度、糖化血红蛋白(HbA1c)的关系。方法T2DM患者98例,按照颈动脉粥样硬化斑块程度分为0级组、1级组、2级组、3级组;按照HbA1c控制水平分为糖尿病A组,糖尿病B组,糖尿病C组,均测定其血清胆红素水平,再进行比较。结果T2DM患者不同程度的斑块分组之间血清胆红素水平存在显著性差异(P<0.05),斑块3级组<2级组<1级组<0级组,不同水平的HbA1c分组之间血清胆红素水平无显著性差异(P>0.05)。结论老年T2DM患者颈动脉粥样硬化斑块形成可能与低血清胆红素有关,血清胆红素可作为老年T2DM患者颈动脉粥样硬化形成的新的实验室诊断指标,而血清胆红素与HbA1c无明显相关。
Objective To explore the relationship of serum bilirubin with carotid athersclerosis and HbA1 c in elderly patients with type 2 diabetes mellitus（T2DM）. Methods Ninety-eight elderly patients with T2DM were divided into 4 groups according to the degree of atheroma, and also divided into 3 groups according to HbAlc level. The serum bilirubin of all the patients were measured and compared. Results The serum bilirubin concentrations were different between the patients with different degrees of atheroma, while there was no significant difference in serum bilirubin concentration among patients with various HbAlc levels （ P 〉 0. 05 ）. Conclusions In elderly patients with T2DM, the formation of carotid plaque might be related to low levels of serum bilirubin, meanwhile there is no relationship between serum bilirubin and HbAlc. We can indirectly assess the athersclerosis in elderly patients with T2DM by testing serum bilirubin.
出处
《实用老年医学》
CAS
2008年第5期358-360,共3页
Practical Geriatrics
