期刊文献+

血清胆红素与冠心病的关系 被引量:2

The relationship between serum bilirubin concentration and coronary heart disease
暂未订购
导出
摘要 目的:探讨血清胆红素浓度与冠心病(CHD)发病的关系。方法:分别检测89例冠心病患者及100例对照者的血清总胆红素(TBIL)、直接胆红素(DBIL)、以及血清总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL),两组均采清晨空腹静脉血。结果:CHD组血清胆红素和HDL浓度低于对照组,差异有显著性(P<0.05)。结论:低血清胆红素可能是CHD的危险因子之一。 Objective:To study the relationship between serum bilirubin concentration and coronary heart disease(CHD).Methods: By early morning samples of venous blood ,serum total bilirubin (TBIL) and direct bilirubin (DBIL) were measured in 89 patients with CHD and 100 normal subjects as control group.The levels of serum total cholesterol (TC),triglycerides (TG) and high density lipoprotein (HDL)were also tested.Results:The concentrations of serum bilirubin and HDLwere lower in the CHD group than those in the control group,the difference was significant(P〈0.05).The concentration of TC and of TG were higher in the CHD group than those of control group (P〈0.05),Conchtsion:Low serum bilirubin concertration mau be one of the risk factors of CHD.
作者 刘传红
出处 《现代医药卫生》 2006年第22期3402-3403,共2页 Journal of Modern Medicine & Health
关键词 冠心病 胆红素 高密度脂蛋白 危险因素 Coronary heart disease Bilirubin High density lipoprotein Risk factors
  • 相关文献

参考文献11

  • 1Schwertner HA,Jackson WG,Tolan G,et al.Awwociation of low serum concentration of bilirubin with increased risk of coronary artery disease[J].Clin Chem,1994,40:18.
  • 2方圻,王钟林,宁田海,邵耕,陈在嘉,陆宗良,李健斋,林传骧,周北凡,诸骏仁,诸永康,陶萍,陶寿淇,龚兰生,顾复生,游凯,戴玉华.血脂异常防治建议[J].中华心血管病杂志,1997,25(3):169-175. 被引量:3069
  • 3Shimada K,Mokuno H,Matsunaga E,et al.Circulating oxidized low-density lipoprotein is an independent predictor for cardiac event in patients with coronary artery disease[J].Atherosclerosis,2004,174:343.
  • 4Kume N,Kita T.Apoptosis of vascular cells by oxidized LDL:involvement of caspases and LOX-1 and its implication in atherosclerotic plaque rupture[J].Circ Res,2004,94:269.
  • 5Zettler ME,Prociuk MA,Austria JA,et al.Oxidized low-density lipoprotein retards the growth of proliferating cells by inhibiting nuclear translocation of cell cycle proteins[J].Arterioscler Thromb Vasc Biol,2004,24:727.
  • 6Weinbrenner T,Cladellas M,Isabel CM,et al.High oxidative stress in patients with stable coronary heart disease[J].Atherosclerosis,2003,168:99.
  • 7Wu TW,Fung KP,Wu J,et al.Antioxdation of human low density lipoprotein by uncojuated and conjugated bilirubins[J].Biochem pharmacol,1996,51:859.
  • 8Arriaga S,Almara A,Mottino A,et al.In vivo anti-complement effect of bilirubin-Ⅸalpha[J].Biochem Pharmacol,2002,64:741.
  • 9Vicente AM,Guillin MI,Alcaraz MJ,et al.Participation of heme oxygenase-1 in a model of acute inflammation[J].Exp Biol Med,2003,228:514.
  • 10Mietus-Snyder M,Friera A,Glass CK,et al.Regulation of scavenger receptor expression in smooth muscle cells by protein kinase C:a role for oxidative stress[J].Arterioscler Thromb Vasc Biol,1997,17:969.

共引文献3068

同被引文献27

引证文献2

二级引证文献10

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部