摘要
目的:探讨血清CEA、CA72-4、CA199的含量对胃癌的临床诊断价值。方法:用电化学发光免疫法对40例胃癌患者进行了血清CEA、CA72-4、CA199的水平测定,并与44例健康人作比较。结果:所有胃癌患者的血清CEA、CA72-4、CA199含量均显著高于正常对照组(P<0.01)。以单一阳性指标作为标准,对胃癌的敏感性分别为28%、40%、33%,特异性分别为77%、91%、86%;联合检验上述3项肿瘤标志物,敏感性为68%、特异性为98%。结论:联合检测的血清CEA、CA72-4、CA199对胃癌的辅助诊断有着较高的临床应用价值。
Objective：To explore the diagnostic value of combined determination of serum CEA, CA72-4 and CA199 levels for gastric cancer. Methods：Serum CEA, CA72-4 and CA199（with ECLIA） levels in 40 patients with gastric cancer and 44 controls. Results： As a single tumor maker for diagnosis, the sensitivity of CEA, CA72-4 and CA199 was 28%, 40 %, 33 % respectively and the specificity was 77 %, 91%, 86% respectively with combined determination of the three markers and as summing three markers positive as diagnostic, the sensitivity would be 68% and specificity would be 98 %. Conclusion：Combined determination of Serum CEA, CA72-4 and CA199 levels could promote the clinical usefulness for diagnosis of gastric cancer.
出处
《数理医药学杂志》
2008年第5期546-547,共2页
Journal of Mathematical Medicine
