摘要
摄取高糖膳食(占总热量80％)第1、3天及第3、5天后,正常人组及高甘油三脂血症组空腹血浆葡萄糖、胰岛素及甘油三酯(TG)含量明显升高(P<0.05及P<0.01);高甘油三酯血症组血浆总胆固醇(TC)及HDL-C明显下降(P<0.05)。摄取高脂膳食(占总热量45％)后,两组TG于第1天,血浆葡萄糖于第5天轻度下降(P<0.05及P<0.01),TC于第3天明显升高(P<0.01);高脂组HDL-C明显下降(P<0.001),对胰岛素水平无影响。作者认为,为防治我国人民以高糖低脂膳食为特点的高脂血症及动脉粥样硬化,应适当降低膳食中糖占总热量的比例。
The fasting Pthema glucose,insulin and liPids response to high-carbohydrate - low-fat dietS and 1ow-Car bohyd rat e-mph-- fatfor in norma1 subjeCtS and patieDts withMnOus hyPertriglyceridenda was ob-SerVed.The normal, mph carbohydrate andop fat dietS consisted of 60%, 80% and40% carbohydrate, 25%, 5% and 45% f8tand 15% pforein of total calorie resPeCti-W1y. Tho faSing p1asma glilcose leveIswtaSed(P<0. 01)on day 1, insulin increa-sed Oll dny 3 (P<0.01 and PM0.05) andTG Ievete tnffeased on dayS 3 and 5 aftertalling op carbohydrate diets both in thenormal tal hypertrigIyberidemic groupe.Th6 haing Plasma TC tal HDLC decreasedon high -- diets mamly in thehy^oppethe peP.Th6 botw Pboma ghcose slightlydecreased on day 5, TG decreased on day1(P<0.05) and TC increased on day 1 ands (P<o.ol ) after taking Ingh fat dids,bat no dmerences were obServed in dri1inlevels.F8Sting p1asma HDL--C IeveIS in thenormal grOup remamed unchanged, butsignificantly decreased 3 dayS after tdrigfugh fat dietS in the hyPertriglyberidem1cgrouP (P<0.001)Our results indiode that nigh carbohy-drate forake may be an imPOrtant cause ofhyPertrig1yCeridemia in our country. ThiBdiet may cause a slight increase in theb1ood glticose level, which in turn Stimulatesan increase in p1asma lipidS and decreaSein HDL--C, whiCh is aSSOciated w1th anincrease in the incident of coronary he8rtdisease. Therefore, to preveni and treathypertriglyberidemis and atheroscleMisin the Cchese POPUlation, wforh is hab1-tUated to a high carbohydeate diet, it isadvisable tO restriCt carbohydrate driakeesPec1a1ly in the m1ddle aged.
出处
《华西医科大学学报》
CAS
CSCD
1990年第2期145-149,共5页
Journal of West China University of Medical Sciences
基金
国家"七.五"重点科技攻关
关键词
膳食
血糖
胰岛素
血脂
High carbohydrate and high fat diets
Normal persons Hypertriglyceridemia
Plasma glucose
Insulin
Plasma lipids
