摘要
目的:探讨低分子肝素钙(LMWH)治疗原发性肾病综合征(NS)并血液高凝状态的疗效。方法:将62例患者随机法分为两组,各31例。两组患儿常规治则同,治疗组患儿在常规治疗基础上给予LMWH。结果:疗程满4周时治疗组尿蛋白定量及血D-二聚体均明显低于对照组(P<0.01);治疗满8周时两组各项指标比较差异均有显著性差异(P<0.01)。治疗期间未见出血倾向。结论:早期LMWH配合激素治疗原发性NS并血液高凝状态疗效显著,临床应用安全、方便。
Objective：To explore the curative effect of low molecular weight heparin for treating primary nephrotic syndrome with hypercoagulability. Methods ：62 patients were ramdomly divided into treatment group （n =31 ）and control group （n = 31 ）. All patients were given routine treatment. The treatment group was treated with low molecular weight heparin too. Results：After 4 weeks＇ treatment, the urine protein excretion and D - dimer were lower in treatment group than those of control group （ P 〈 0.01 ）. After 8 weeks＇ treatment, the differences of all indexes between two groups were significant （P 〈 0.01 ）. There was no tendency of bleeding. Conclusion：Low molecular weight heparin combined with glucocorticoid is remarkable, safe and convenient at the early period of primary nephrotic syndrome with hypercoagulability.
出处
《现代临床医学》
2008年第5期339-340,共2页
Journal of Modern Clinical Medicine
关键词
肾病综合征
血液
高凝状态
低分子肝素钙
nephrotic syndrome
blood
hypereoagulability
low molecularweight heparin
