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天津市2007年健康人群乙型脑炎抗体水平监测分析 被引量:10

Surveillance and analysis of healthy people′s antibody against Japanese encephalitis in Tianjin in 2007
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摘要 目的:分析2007年天津市健康人群乙型脑炎抗体水平特征及影响因素。方法:在天津市采集7个年龄组,各30名以上调查对象,于2007年5月份和11月份分别进行调查并采集血清标本,应用ELISA法对乙脑特异性IgG抗体进行定量检测。结果:天津市健康人群5月份乙脑抗体阳性率为40.46%,11月份为38.46%,流行季节前后抗体阳性率无统计学差异(P>0.05)。不同年龄组人群乙脑抗体阳性率存在统计学差异,其中7岁以下年龄组的抗体阳性率显著高于7岁及以上年龄组(P<0.001)。免疫前后抗体阳性率有统计学差异(P<0.001)。结论:天津市健康人群乙脑抗体水平主要受疫苗接种影响,由流行季节造成的显隐性感染有限。乙脑疫苗接种是我市预防乙脑疫情最有效的途径,在抓好适龄儿童乙脑疫苗接种工作质量的同时,适时开展针对7岁及以上人群接种,可降低高危人群的易感危险。 Objective:To test and analyze the antibody against Japanese encephalitis of healthy people in Tianjin in 2007.Methods:Collecting 388 samples of blood serum before the Japanese encephalitis epidemic season and 325 shares after the epidemic season in some hospitals around the health people.Using ELASA method to test the IgG antibody against Japanese encephalitis quantitatively.Results:The positive test on antibody against Japanese encephalitis between pre-epidemic season and post-epidemic season shows no difference.The test results of the under-sevens is higher than above.The test result of vaccinated people is higher than unvaccinated people.Conclusion:The positive result on healthy people's antibody against Japanese encephalitis in Tianjin in 2007 is not high.The result is mainly effected by vaccination and securely by inapparent infection.Vaccination is the most efficient way to prevent Japanese encephalitis under-sevens at present in Tian Jin.Developing direction vaccination above-sevens who is to be under the dangerous circumstances is necessary.
出处 《中国卫生检验杂志》 CAS 2008年第9期1850-1851,1875,共3页 Chinese Journal of Health Laboratory Technology
基金 天津市科技支撑计划重大项目基金资助课题(07SYSYSF05100)
关键词 流行性乙型脑炎 抗体 监测 Japanese encephalitis Antibody Surveillance
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