摘要
目的比较不同型号卡波姆的流变学性质。方法测定不同条件下卡波姆凝胶的流变学性质及卡波姆的热分析性质。结果两个型号的卡波姆凝胶均为假塑型流体,卡波姆凝胶934的黏度比卡波姆1342凝胶的黏度更易受金属离子及有机溶剂的影响。结论不同型号的卡波姆凝胶具有不同的流变学性质,在制剂应用中应合理选用。
Objective To compare the rheological properties of different types of carbomer. Methods The rheological and thermal properties of carbomer were measured under different conditions. Results Both of carbomer gels were pseudoplastic fluids, and carbomer 934 gel was more sensitive to the influence of ions and organic solvents than carbomer 1342 gel. Conclusion The different types of carbomer have different rheological properties and they should be selected reasonably in pharmaceutical application.
出处
《中国药业》
CAS
2008年第19期38-39,共2页
China Pharmaceuticals
关键词
卡波姆
黏度
流变性
差示扫描量热分析
carbomer
viscosity
rheology
differential scanning calorimetry （DSC）
