摘要
为探讨曼尼希碱及曼尼希碱型前药的研究现状,系统查阅了近几年曼尼希碱及曼尼希碱型前药在医药和生物碱合成中的作用等文献,总结归纳出曼尼希碱及曼尼希碱型前药具有某些活性,能改善药物的理化性质,指出曼尼希碱及曼尼希碱型前药具有广泛的应用价值和经济价值。
Discussion of present research status of Mannich bases and Mannich base-prodrugs is based on consulting the effect of the Mannich bases and Mannich base-prodrugs on synthesis of medicine and alkaloids reported in literatures,and the summary and induction from them indicate that Mannich bases and Mannich base-prodrugs have some avtivities and can improve the physical and chemical properties of the drugs. Mannich bases and Mannich base-prodrugs possess extensive application value and economical value.
出处
《河北工业科技》
CAS
2008年第5期315-317,320,共4页
Hebei Journal of Industrial Science and Technology
基金
河北省科技攻关项目(05276431)
关键词
曼尼希碱
曼尼希碱型前药
医药
合成
Mannich bases
Mannich base-prodrugs
medicine
synthesis
