摘要
目前以不锈钢和钴铬合金为基础的药物洗脱支架不能从根本上解决亚急性血栓形成和再狭窄的问题。于是,生物可吸收支架开始成为关注的焦点和热点。目前临床上研究的可吸收金属支架主要成分是镁合金,包括93%镁,7%稀土元素。它具有新生内皮化快速、低致血栓性和合适的降解时间(两三个月)优点。所以,新型冠状血管内生物可吸收支架是未来支架的发展方向,是目前冠心病介入治疗最前沿的课题。
The problem of subacute thrombosis and restenosis is still not being resolved with stainless steel and cobalt-chromium alloy-based drug-eluting stent fundamentally. Therefore, the bioabsorbable stent has become the focus of attention. At present, the main component of the bioabsorbable metal stent studying in clinic is magnesium alloy, including 93% magnesium, 7% REE （rare-earth elements）. It has a new endothelial recovery fast, low-induced thrombosis and the degradation of suitable time （2-3 months）, and other advantages. The bioabsorbable coronary stent is the future direction of stent development.
出处
《中国组织工程研究与临床康复》
CAS
CSCD
北大核心
2008年第35期6997-7000,共4页
Journal of Clinical Rehabilitative Tissue Engineering Research
基金
a grant from the National High Technology Research and Development Program of China(863 Program),No.2006AA02Z4Z3~~
