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软骨肉瘤嗜银蛋白与病理分级和预后的关系

Investigation of iodine and thiocyanates in blood and urine with simple goiter patients
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摘要 作者采用银染技术对30例软骨肉瘤的核仁组成区嗜银蛋白进行测定,并结合病理学资料和临床随访,评估其与病理分级及预后的价值。结果显示:死亡病例软骨肉瘤的嗜银蛋白平均数(17.432±0.728)明显高于非死亡病例软骨肉瘤乎均数(7.835±0.972);不同病理学分级的嗜银蛋白数有显著性差异,分化好的肿瘤,嗜银蛋白计数低。提示嗜银蛋白可以反映软骨肉瘤的恶性潜能,可较好地区别不同分级的软骨肉瘤,同时也是一项较好的预后参考指标。 Iodine and thiocyanates in blood and urine were measured in 43 patients with simple goiter and 23 normal contros. The results showed that: (1) The level of urinary iodine in control was within the range of national standard. (2) The level of bloocl iodine in patients with simple goiter was mild lower than control.The level of urinary iodine and thiocyanates in blood and urine were significantly higher(P< 0. 05 ~ 0. 01);the ratio of urinary iodine/thiocyanates was significantly lower than those in control. The patients with simple goiter in Ningbo area occur in sporadic form, 20%cases were caused by inadequte dietary intake of iodine,80% were associated with other causes. High thiocyanates levels and low ratio of urinary iodine/thiocyanates may be one of the pathogenic factors.
机构地区 宁波市第一医院
出处 《宁波医学》 1997年第6期254-255,共2页
关键词 软骨肉瘤 嗜银蛋白 病理学 分级 预后 Iodine Thiocyanate Simple goiter
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参考文献1

  • 1D. Ploton,M. Menager,P. Jeannesson,G. Himber,F. Pigeon,J. J. Adnet. Improvement in the staining and in the visualization of the argyrophilic proteins of the nucleolar organizer region at the optical level[J] 1986,The Histochemical Journal(1):5~14

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