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超声二维斑点追踪显像评价肥厚型心肌病左心室扭转和径向位移的初步研究 被引量：4

Initial exploration of evaluation of left ventricular twist and radial displacement in patients with hypertrophic cardiomyopathy by speckle-tracking imaging
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摘要 目的采用超声二维斑点追踪显像技术（STI）探讨肥厚型心肌病（HCM）患者左室扭转运动的特征。方法随机选取心功能测值正常的HCM患者及正常对照各35例，取胸骨旁左室心尖和心底短轴观二维图像对左室旋转及径向位移进行测量分析，记录并计算心底部旋转角度峰值（Prot-MV）、心尖部旋转角度峰值（Prot-AP）、扭转角度峰值（Ptw）、收缩期末扭转角度（AVCtw））、等容舒张期末扭转角度（MVOtw）、解旋率（UntwR）、解旋减半时间（HTU）、收缩期末径向位移（AVCdisp）、等容舒张期径向位移（IVRTdisp），比较两组间上述各参数的差别；同时构建左室扭转-径向位移环，并分析其各形态参数。结果①与对照组比较，HCM组Prot-MV、Prot-AP、Ptw、AVCtw、MVOtw、HTU测值均增加，UntwR测值减低，两组间差异均有统计学意义（P均〈0．05），而AVCdisp、IVRTdisp测值差异无统计学意义。②HCM组内左室旋转心尖部达峰时间较心底部测值增加，差异有统计学意义（P〈0．05）。③与对照组比较，HCM组收缩期及等容舒张期左室扭转-径向位移环的变化斜率均增加，差异均有统计学意义（P均〈0．05）。结论STI显示HCM患者左室旋转运动力学参数较正常人有明显异常改变。 Objective To evaluate the left ventricular twist and radial displacement in patients with hypertrophic cardiomyopathy（HCM） by 2-dimensional（2D） ultrasound speckle-tracking imaging（STI）. Methods 2D images of left ventricle at basal and apical short axis views were acquired in 35 patients with HCM and 35 healthy subjects,and then were analysed off line to assess left ventricular（LV） rotation and radial displacement. Peak rotation （Prot） and the time to peak rotation in basal and apical short axis views were measured separately. Peak twist （Ptw）, twist at aortic valve closure（AVCtw）, twist at mitral valve opening（MVOtw）, untwisting rate （Untw R）,half time of untwisting（HTU）, radial displacement were also calculated and compared and compared between HCM group and the control group. Based on the value of radial displacement, the LV twist-displacement loop was established and the features of the loop were analyzed. Results ①Compared with the control group,the value of Prot-MV, Prot AP, Ptw, AVCtw, MVOtw and HTU increased significantly （all P 〈0. 05） and the Untw R decreased （ P 〈0.05） in the HCM group. ②In HCM group,time to Prot in apical view was higher than that in basal. ③Twist-displacement loops could be constructed noninvasively. The liner slope changed significantly in HCM group compared with that of the control group. Conclusions The characteristics of LV rotation in patients with HCM were significantly different from the normals,and the STI measurement could be used noninvasively to evaluate the characteristics of LV twist and radial displacement.
作者 张丽 谢明星 王新房 吕清 韩伟 张静 刘莹莹 陈明 王蕾
机构地区 华中科技大学同济医学院附属协和医院超声诊断科湖北省分子影像重点实验室
出处 《中华超声影像学杂志》 CSCD 2008年第8期645-648,共4页 Chinese Journal of Ultrasonography
关键词 超声心动描记术 心肌病 肥厚性 心室功能 左 扭转 斑点追踪显像 Echocardiography Cardiomyopathy, hypertrophic Ventricular function, left Torsion Speckle tracking imaging
分类号 R686 [医药卫生—骨科学]
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参考文献10

  • 1Alaclai R, Seidman JG, Seidman CE, et al. Genetic basis of hypertrophic cardiomyopathy:from bench to the clinics. J Cardiovasc Elect rophysiol, 2008,19 : 104-110.
  • 2Bottinelli R, Coviello DA, Redwood CS, et al. A mutant tropomyosin that causes hypertrophic cardiomyopathy is expressed in vivo and associated with an increased calcium sensitivity. Circ Res, 1998,82 : 106-115.
  • 3Young AA, Kramer CM, Ferrari VA, et al. Three-dimensional left vent ricular deformation in hypertrophic cardiomyopaihy. Circulation, 1994,9(1 : 854-867.
  • 4Rademakers FE, Buchaher MB, Rogers WJ, et al. Dissociation between left ventricular untwisting and filling: accentuation by catecholamines. Circulation, 1992,85 : 1572-1581.
  • 5张丽,谢明星,i瓶莠,吕清,韩伟,张静,卢晓芳,王静,杨亚利,李玲,刘莹莹,张玲利,李朝军.超声二维斑点追踪显像技术评价不同年龄正常成人左心室扭转运动的初步研究[J].中华超声影像学杂志,2007,16(9):746-750. 被引量：31
  • 6Rust EM, Albayya FP, Metzger JM. Identification of a contractile deficit in adult cardiac myocytes expressing hypertrophic cardiomyopathy-associated mutant troponin T proteins. J Clin Invest, 1999,103:1459-1467.
  • 7Langeland S,D'hooge J ,Wouters PF,et al. Experimental validation of a new ultrasound method for the simultaneous assessment of radial and longitudinal myocardial deformation independent of insonation angle. Circulation, 2005,112 : 2157-2162.
  • 8Dong S, Hees P, Siu C, et al. MR1 assessment of LV relaxation by untwisting rate: a new isovolumic phase measure of tau. Am J Physiol Heart Circ Physiol, 2001,281 : H2002- H2009.
  • 9Serri K,Reant P, Lafitte M, et al. Global and regional myocardial function quantification by two dimensional strain: application in hypertrophic cardiomyopathy. J Am Coil Cardiol, 2006,47 : 1175- 1181.
  • 10熊润青,谢明星,王新房,吕清,王静,卢晓芳,杨亚俐,贺林,王瑶,刘夏天,张静,龙莎,龚静吉.超声组织同步显像技术评价肥厚性心肌病患者心肌收缩协调性的初步研究[J].中华超声影像学杂志,2006,15(3):164-167. 被引量：5

二级参考文献24

  • 1金玉,许迪,陆凤翔,周蕾,雍永宏,陈莉.应用定量组织速度成像评价肥厚型心肌病患者心功能[J].中华超声影像学杂志,2004,13(7):485-487. 被引量：9
  • 2罗安果,尹立雪,李春梅,王莲春,林家弟,蔡雁朗,孟庆国.超声斑点跟踪显像技术对左心室收缩期旋转角度的初步研究[J].中华超声影像学杂志,2006,15(9):641-645. 被引量：35
  • 3Hayashida W,Kumada T,Kohno F,et al.Left ventricular regional relaxation and its nonuniformoty in hypertrophic nonobstructive cardiomyopathy.Circulation,1991,84:1496-1504.
  • 4Losi MA,Betocchi S,Grimaldi M,et al.Heterogeneity of left ventricular filling dynamics in hypertrophic cardiomyopathy.Am J Cardiol,1994,73:987-990.
  • 5Sengupta PP,Mehta V,Mohan JC,et al.Regional myocardial function in an arrhythmogenic milieu:tissue velocity and strain rate imaging in a patient who had hypertrophic cardiomyopathy with recurrent ventricular tachycardia.Eur J Echocardiogr,2004,5:438-442.
  • 6Betocchi S,Hess OM,Losi MA,et al.Regional left ventricular mechanics in hypertrophic cardiomyopathy.Circulation,1993,88:2206-2214.
  • 7Penicka M,Bartunek J,De Bruyne B,et al.Improvement of left ventricular function after cardiac resynchronization therapy is predicted by tissue Doppler imaging echocardiography.Circulation,2004,109:978-983.
  • 8Cardim N,Castela S,Cordeiro R,et al.Tissue Doppler imaging assessment of long axis left ventricular function in hypertrophic cardiomyopathy.Rev Port Cardiol,2002,21:953-985.
  • 9Cardim N,Longo S,Ferreira T,et al.Tissue Doppler imaging assessment of long axis left ventricular function in hypertensive patients with concentric left ventricular hypertrophy:differential diagnosis with hypertrophic cardiomyopathy.Rev Port Cardiol,2002,21:709-740.
  • 10Dong SJ,MacGregor JH,Crawley AP,et al.Left ventricular wall thickness and regional systolic function in patients with hypertrophic cardiomyopathy:a three-dimensional tagged magnectic resonance imaging study.Circulation,1994,90:1200-1209.

共引文献34

同被引文献61

  • 1阎国辉,智光.心脏扭转运动的研究进展[J].临床超声医学杂志,2007,9(1):41-43. 被引量：4
  • 2Schneider M. SonoVue, a new ultrasound contrast agent. Eur Radiol, 1999,9 :S347-S348.
  • 3Notorni Y, Lysyansky P, Setser RM, et al. Measurement of ventricular torsion by two-dimensional ultrasound speckle tracking imaging. J Am Coll Cardiol,2005,45:2034-2041.
  • 4Unger EC, Hersh E,Vannan M,et al. Local drug and gene delivery through microbubbles. Prog Cardiovasc Dis, 2001,44 : 45-54.
  • 5Price RJ, Skyba DM, Kaul S, et al. Delivery of colloidal particles and red blood cells to tissue through microvessel ruptures created by targeted microbubble destruction with ultrasound. Circulation, 1998,98:1264-1267.
  • 6Wang W,Bian Z,Wu Y,et al. Bioeffects of low-frequency ultrasonic gene delivery and safety on cell membrane permeability control. J Ultrasound Med, 2004,23 ; 1569-1582.
  • 7Song J, Chappell JC, Qi M, et al. Influence of injection site, microvascular pressure and ultrasound variables on microbubblemediated delivery of microspheres to muscle. J Am Coll Cardiol,2002,39:726-731.
  • 8Buckberg G. Basic science review:the helix and the heart. J Thorac Cardiovasc Surg, 2002,124: 863-883.
  • 9Zhao W, Choi JH, Hong GR, et al. Left ventricular relaxation. Heart Failure Clin,2008,4:37-46.
  • 10Sutherland GR, Di Salvo G,Claus P, et al. Strain and strain rate imaging: a new clinical approach to quantifying regional myocardial function[J]. J Am Soc Echocardiogr, 2004, 17 (7) :788-802.

引证文献4

二级引证文献9

中华超声影像学杂志
2008年 第8期

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