摘要
目的应用超声斑点追踪显像技术评估新生儿至老年人左心室扭转运动随年龄增加的变化特点，并建立不同年龄组的正常参考值。方法使用二维超声心动图采集293例15d至72岁健康志愿者左室心尖和心底短轴观图像，斑点追踪显像软件脱机分析左室扭转运动，比较不同年龄组的心尖旋转角度峰值（PAr）、基底旋转角度峰值（PBr）、扭转角度峰值（Ptw）、标化左室长度后扭转（PtwN）、解旋速度峰值（PutwV）、等容舒张期解旋百分比（1utw％）。结果293例受试者中274例获得左室扭转运动数据。左室扭转随年龄增加而变化：Ptw随年龄增加而增大；3岁以前和25～45岁间的PtwN显示为最大；PutwV从出生至25岁以前随年龄增加，25-45岁保持在相近水平，45岁以后随年龄减小。lutw％在3岁以前最低，3～45岁随年龄逐渐增加，45岁以后随年龄增加而减小。结论超声斑点追踪显像能无创、较准确地评估左室扭转运动，左室扭转运动随年龄增加的变化反映了新生儿至老年人左室扭转生物力学的成熟和适应性调整过程。
Objective To assess the characteristic of left ventricular（LV） twist changed from infancy to the elder,in order to determine the normal value of LV twist in different age group. Methods After acquired basal and apical LV short-axis images in 293 healthy volunteers （aged 15 days to 72 years） by 2- dimensional echocardiography, speckle tracking echocardiography was used to analysis LV twist motion offline. The peak apical rotation （ PAr）, peak basal rotation （ PBr）, peak LV twist （ Ptw）, peak LV twist normalized by LV length （ PtwN）, peak untwisting velocity （ PutwV）, isovolumic untwisting % （ lutw % ） in different group were compared. Results Reliable LV twist measurements were obtained in 274 volunteers. Different LV twist values were noted according to age. Ptw increased gradually with advancing age, when normalized by LV length, PtwN showed higher values before 3 years old and 25 to 45 years old. PutwV increased with aging from infancy to 25 years old, and leveled off from 25 to 45 years old, then decreased with advancing age. lutw% was lowest before 3 years old,and increased gradually from 25 to 45 years old, then decreased with aging. Conclusions speckle tracking echocardiography can be used to noninvasively and exactly assess LV twist with high feasibility. The effect of aging on LV twist may reflect the process of maturational and adaptive modulation of LV torsional biomechanics from infancy to the elder.
出处
《中华超声影像学杂志》
CSCD
2008年第5期369-373,共5页
Chinese Journal of Ultrasonography
