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氯胺酮复合咪达唑仑静脉麻醉在各年龄段地震创伤手术中的应用

Application of Ketamine-midazolam Intravenous Anesthesia in Patients with Different Ages Undertaking Earthquake Trauma Operation
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摘要 目的观察氯胺酮复合咪达唑仑静脉麻醉在各年龄段地震创伤手术中的应用效果。方法因地震创伤急需行清创术的伤员56例,按年龄段分为三组,通过静脉依次给予咪达唑仑0.05~0.1mg/kg、氯胺酮1~2mg/kg,术中据情况追加氯胺酮0.5~1mg/kg。观察记录各组伤员术中MAP、HR、R及SPO2的变化,记录诱导及苏醒时间以及术中和术后发生不良反应的情况。结果各组伤员术中MAP、HR、R及SPO2维持较为平稳,诱导及苏醒均较为迅速,术中及术后不良反应发生较少。结论氯胺酮复合咪达唑仑静脉麻醉可为地震创伤手术提供一种安全、有效及副作用少的麻醉方法。 Objective To observe the clinical effect of ketamine-midazolam intravenous anesthesia in patients with different ages undertaking earthquake trauma operation. Methods Fifty-six earthquake victims treated with debridement were divided into three age groups. Midazolam 0.05 - 0.1mg/kg and ketamine 1 - 2mg/kg intravenous injection were used for induction and maintenance of anesthesia. Repeat Ⅳ ketamine dose of 0.5 - 1.0mg/kg were given for prolonged procedures. The mean arterial pressure(MAP),heart rate(HR), respiratory frequency (R) and Pulse Oxygen Saturafion(SPO2) during anesthesia were recorded. The induction time and consciousness recovery time were recorded. The side-effect during ansesthesia were investigated. Results The MAP,HR ,R and SPO2 were stable in the three groups. The induction time recovery time in each group was short. No severe side-effect happened in all groups. Gonelusion Ketamine-midazolam intravenous anesthesia is safe, effective and with a low incidence of major adverse effcts for patients with different ages undertaking earthquake trauma operation.
出处 《中国现代医生》 2008年第25期27-28,30,共3页 China Modern Doctor
关键词 氯胺酮 咪达唑仑 静脉麻醉 地震 年龄 Ketamine Midazolam Intravenous anesthesia Earthquake Age
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