摘要
目的评价不同检测系统血小板(PLT)计数结果的偏差及临床可接受范围。方法根据美国临床实验室标准化委员会(NCCLS)EP-9A2文件要求,每天选取8例标本,分别在3个检测系统上进行PLT测定,共测定8 d,记录结果。对所测结果进行统计分析,计算和评价其系统间的偏差。以Beckman Coulter(LH750 System为比较检测系统,Sysmex XT-1800i和Coulter Ac.T5 diff为实验检测系统进行方法学比较,计算相对偏差,以1/3 CLIA’88规定的允许误差为标准进行评估。结果Coulter(LH750 System与XT-1800i的相关系数(r)=0.999,回归方程为^Y=0.995X-2.209;Coulter(LH750 System与Coulter Ac.T5diff的r=0.997,回归方程为^Y=1.006X-1.108。结论3种系统检测PLT的偏差在临床可接受范围内,结果具有可比性。
Objective To evaluate bias and clinical acceptability of platelet results among different detection systems. Methods According to the profile of NCCLS EP-9A2 document, 8 samples were chosen to test platelet count on 3 equipments for 8 days. Results were analyzed and the bais among three equipments was evaluated. Coulter RLH 750 System was set as the comparison system, while Sysmex XT-1800i and Coulter Ac. T5 diff were set as the laboratory systems. Relative bias was computed by medical decision level of platelet. With 1/3 CLIA＇88 permissive error the biases of the two laboratory systems as the standard were evaluated. Results The correlation coefficient of LH 750 System and Sysmex XT-1800 was 0. 999,and the regression equation was Y= 0. 995X-2. 209;the corelation coefficient of LH 750 System and Ac. T5 diff was 0. 997, the regression equation was 7= 1. 006X--1. 108. Conclusion The biases of platelet count among three equipments are in the clinical acceptable range and the result comparibility among them is exist.
出处
《国际检验医学杂志》
CAS
2008年第8期691-692,694,共3页
International Journal of Laboratory Medicine
关键词
血小板计数
设备和供应
偏差
比较研究
Platelet count
Equipment and supply
Bias
Comparative study
