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新型巯基探针的合成与光谱性质研究 被引量:1

Research on synthesis and photo-physical properties of novel sulfhydryl-reactive fluorescent probes
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摘要 以苯基苯并咪唑作为荧光发射团,合成了三种检测巯基的新型荧光化合物.在基本荧光发射团上分别引入了羧酸基;酯基;双键活性基团.提高了探针分子的水溶性,脂溶性和生物相容性.并探索研究了与巯基类化合物反应后的光谱特性. A convenient method to synthesize three kinds of novel 2-(2-hydroxyphenyl) benzimidazole in order to improve the solubilities of the fluorophores with substituent(s) of carboxyl, ester and double-bond which are aimed for determining the sulfhydryl group was reported. The corresponding photo-physical properties were characterized by ultraviolet absorption and fluorescence spectra in methanol.
出处 《吉林化工学院学报》 CAS 2008年第3期12-15,21,共5页 Journal of Jilin Institute of Chemical Technology
基金 国家自然科学基金资助项目(20771082)
关键词 苯并咪唑 荧光特性 巯基探针 合成 benzimidazole fluorescent property SH sulfhydryl-reactive probes synthesis
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