摘要
目的评价美国Active TbDetect ELISA System诊断试剂盒诊断活动性肺结核的敏感性,特异性和重复性。方法采用Active酶联免疫诊断试剂盒对51例结核病人和70例健康对照的血清标本进行检测,同时与国产试剂进行平行比较分析。结果采用Active试剂,检测结核病人的敏感性为76.5%,特异性为64.3%。与国产试剂进行平行比较,敏感性和特异性方面无显著性的差别。不同实验室对相同标本的检测结果显示,Active试剂盒具有很好的重复性。结论Active试剂盒对诊断活动性肺结核有一定作用,临床应结合其他检验结果进行综合分析。
Objective To evaluate the sensitivity, specificity and repeatability of active diagnosis assay for the diagnosis of pulmonary tuberculosis. Methods We measured the level of IgG of serum by using the active ELISA diagnosis assay in 51 patients and 70 healthy donors, and made a parallel comparison with the assay made in China. Results The sensitivity and specificity of active assay for the diagnosis of pulmonary tuberculosis were respectively 76. 5% and 64.3%. Comparing the assay made in China, no significant difference of sensitivity and specification was observed by the active ThDetect ELISA system assay. Testing the same samples in different laboratories, the active ThDetect ELISA system assay showed a good repetition. Conclusion In the diagnosis of active pulmonary tuherculsis, the active TbDetect ELISA system assay is efficient. The result must be analyzed synthetically with other results in clinical research.
出处
《临床肺科杂志》
2008年第10期1256-1257,共2页
Journal of Clinical Pulmonary Medicine
关键词
结核
诊断
敏感性
特异性
tuberculosis
diagnose
sensitivity
specificity
