摘要
[目的]观察复方丹参对放射线引起心脏损伤的保护作用。[方法]38例胸中下段食道癌病人随机分为单纯放疗组和配合应用复方丹参组各19例及19例,动态观察放疗前后及放疗后3月、1年的心电图和心肌酶学变化。[结果]单放组治疗后心电图异常率明显高于治疗前(P﹤0.05),且以心律失常和缺血型ST-T改变为主,心肌酶学变化不明显。复方丹参组治后心电图异常发生率明显低于单放组(P﹤0.05)。[结论]复方丹参对放射线对心脏的损伤有保护作用。
[Objective] To observe the protective function of composite salvia miltiorrhiza to the heart damages caused by radioactive rays. [ Methods] Overall 38 patients with middle or lower thoracic esophageal carcinomas were randomly divided into the pure radiotherapy group and coordinate application composite salvia miltiorrhiza group, 19 examples in each group. Dynamically observed the changes of electrocardiogram （ECG） and cardiac creatase before and after radiotherapy and after radiotherapy for 3 months and 1 year. [Results] The abnormal ECG was obviously higher than before the treatment in the pure radiotherapy group （P 〈 0.05）, especially for arrhythmia and ST-T change. But the change of cardiac ereatase was not obvious. The abnormal ECG was obviously degraded after the treatment in the combination group. [Conclusion] Composite salvia miltiorrhiza have the function of protecting heart injury from radioactive rays.
出处
《现代预防医学》
CAS
北大核心
2008年第17期3460-3461,3463,共3页
Modern Preventive Medicine
关键词
复方丹参
心脏损伤
食道癌
放疗
Composite salvia miltiorrhiza
Heart injury
Esophageal carcinoma
Radiotherapy
