摘要
为探讨小儿幽门螺杆菌（ＨＰ）感染诊断的最佳手段，对９８例不同群体小儿用胃粘膜活检标本尿素酶快速诊断法、血清ＨＰ－ＩｇＧ测定法、胃液ＨＰ－聚合酶链反应（ＰＣＲ）法进行了ＨＰ感染的对比性研究。结果：三种方法在上消化道疾病组胃粘膜活检标本中ＨＰ感染阳性率分别为４２％、５４％、４８％，与非消化道疾病及健康小儿对照组差异有显著性意义（Ｐ＜０．００５）。结果表明：三种方法在检测ＨＰ的阳性率方面无明显差别，而胃液ＨＰ－ＰＣＲ法方法简单实用、敏感性和特异性均较好，可作为诊断ＨＰ感染的最佳方法之一。
To search for the best diagnostic approach to Helicobacter pylori (HP) infection in children. The authors conducted a comparative study on gastric mucosa′s urease test, serum HPIgG antibody and gastric juice HPPCR in 98 children. The results showed that in the cases with upper gastrointestinal (GI) tract diseases, the urease test, HPIgG and HPPCR were positive in 42%、 54% and 48%, respectively. The difference among the groups with upper GI tract disorders, nonupper GI tract disorders and the healthy children was significant. Of the 3 diagnostic methods, HPPCR was found a simpler, more sensitive, and more practical one.
出处
《中华儿科杂志》
CAS
CSCD
北大核心
1997年第12期639-640,共2页
Chinese Journal of Pediatrics
