摘要
目的:观察并探讨复方消疲悦意饮对实验性慢性疲劳大鼠行为学的影响。方法:将大鼠随机分为正常组(8只)和造模组(16只),造模组复制慢性疲劳模型后再随机分为模型组(8只)和中药组(8只),中药组给予复方消疲悦意饮灌服。采用Open-Field法、鼠尾悬挂及力竭游泳实验评价所有实验大鼠的行为学变化。结果:造模组造模后大鼠水平及垂直运动次数明显减少,力竭游泳时间缩短,鼠尾悬挂不动时间延长(P<0.05),给予复方消疲悦意饮灌服后以上各参数明显改善(P<0.05)。结论:复方消疲悦意饮具有明显改善慢性疲劳的作用。
Objective： To explore and discuss the effect of Xiaopi Yueyi formula on behavioral changes in rats with chronic fatigue syndrome. Methods： 24 rats were divided into group model（ 16 rats） and control （8 rats） at random, and after produced rats with chronic fatigue syndrome, half in the former were taken orally with Xiaopi Yueyi formula while the latter were taken equally normal saline, moreover, methods of Open-Field,tail suspend time and exhaust swimming time were estimated and evaluated. Results： After succeeding in chronic fatigue manifestation in rats of group model, number of parallel and vertical movement diminished markedly, furthermore, time of tail suspend and exhaust swimming prolonged apparently. Nevertheless, Xiaopi Yueyi formula could ameliorate significantly these parameters in rats（P 〈 0.05）. Conclusion： Xiaopi Yueyi formula could ameliorate significantly chronic fatigue syndrome in rats.
出处
《医学研究生学报》
CAS
2008年第8期817-819,共3页
Journal of Medical Postgraduates
关键词
复方消疲悦意饮
慢性疲劳综合征
行为学
大鼠
Xiaopi Yueyi formula
Chronic fatigue syndrome
Behavioral changes
Rat
