摘要
目的:比较两种吻合方法建立静脉桥狭窄动物模型的差别。方法:2.0～2.5kg普通新西兰大白兔17只,分A、B两组,取颈外静脉与颈总动脉进行端端吻合,吻合时分别采用间断吻合(A组)和间断加连续吻合(B组)的方法。术后1月取下静脉桥,采用计算机图像处理系统分析新内膜、中膜厚度。结果:A组手术时间和吻合时间均较B组长,出血多,具有统计学意义;1月后两组静脉桥管壁均增厚,光镜下见新内膜形成,中膜增厚,两组差异没有显著性。结论:间断加连续端端吻合兔颈外静脉-颈总动脉,建立静脉桥模型要优于单纯间断吻合方法。
Objective：To compare two type of anastomosis to institute vein graft model. Methods：Studies were performed by using normal New Zealand＇s white rabbits（n=17,weight 2,0 -2.5kg） which be divided into two group, Every rabbit＇s unilateral jugular vein was anastomosed end-to-end with common carotid artery by interrupted suture（group A,n=9）or interrupted and continuous suture（group B,n=8）, Samples of tissues were harvested after 1 mouth and examined under a light microscope, The vessel wall dimensions were measured by computer-aided planimentry. Results：The time of anastomosis and whole operation of group A are longer than group B（P〈0.05）.The bleeding of group A is more than Group B（P〈0.05）,All vien grafts are unobstructed and the total wall thickening. The neointimal and medial demostracted hyperplasia. But there is not statistically difference between the two goups, Conclusion：The method of anastomosis by interrupted and continuous suture is successfully and excelled that by single interrupted suture.
出处
《重庆医科大学学报》
CAS
CSCD
2008年第8期994-996,共3页
Journal of Chongqing Medical University
关键词
动物模型
吻合方法
兔
静脉桥
再狭窄
Animal model
Method of anastomosis
Rabbit
Vein graft
Restenosis
