摘要
目的探讨健康人角膜滞后量和阻力因子量测量值及其与中央角膜厚度、角膜曲率、等效球镜度数及眼压之间的相互关系。方法横断面研究。每名研究对象任选一眼的检测数据进行分析，共计205只眼。眼反应分析仪测量角膜滞后量和阻力因子量，并用多重回归分析其与中央角膜厚度、角膜曲率、等效球镜和眼压之问的相互关系。结果205只眼的角膜滞后量和阻力因子量呈正态分布，两者集中分布在8．1～11．0mmHg（1mnqHg=0．133kPa）之间。在不同性别以及年龄（〈25岁和1〉25岁）组间的角膜滞后量和阻力因子量差异均无统计学意义（P〉0．05）。205只眼角膜滞后量和阻力因子量的95％参考值范围分别是6．8～13．0和6．6～13．6mmHg。角膜滞后量和阻力因子量与中央角膜厚度、角膜曲率、等效球镜度数及眼压相关（P〈0．05）。结论角膜滞后量和阻力因子量分别描述了角膜生物力学特性中的不同属性，两者可能是对角膜厚度、曲率、硬度、水化状态、眼压等因素作用效力的综合体现。本文测定了正常人眼角膜滞后量和阻力因子量值，为今后进一步研究角膜滞后量和阻力因子量与眼病之问的关系奠定了基础。
Objective The aim of this study was to investigate the corneal hysteresis （CH） and corneal resistance factor（CRF） in normal eyes and to determine their relationship between central corneal thickness（ CCT）, corneal curvature, sphere equivalence （SE） and intraocular pressure （IOP）. Methods Cross-sectional study. This study included 205 normal eyes （205 patients）. Ocular Response Analyzer （ORA, Reichert Ophthalmic Instruments, New York, USA ） was used to measure CH and CRF. Multivariate regression analysis was applied to study their relationship between CCT, corneal curvature, SE, lOP （ noncontact tonometer）. Results The values of CH and CRF in 205 eyes presented normal distribution and concentrated on 8. 1 to 11.0 mm Hg（ 1 mm Hg =0. 133 kPa）. No statistical significant difference was found in both CH and CRF of different gender and ages （ 〈 25 years or 〉125 years） （P 〉 0. 05 ）. 95% reference interval of CH and CRF in 205 eyes were 6. 8 to 13.0 mm Hg and 6. 6 to 13.6 mm Hg. The correlation of CH and CRF with CCT, corneal curvature, SE and lOP were significant （P 〈 0. 05 ）. Conclusion CH and CRF measure different biomechanical aspects of cornea, they may reflect the combined effect of CCT, corneal curvature, rigidity, hydration and IOP. These values of CH and CRF in normal eyes established foundation to further investigate their relationship with eye diseases.
出处
《中华眼科杂志》
CAS
CSCD
北大核心
2008年第8期715-719,共5页
Chinese Journal of Ophthalmology
