摘要
目的:探讨川芎嗪致不良反应的一般规律及特点,为临床合理用药提供参考。方法:对国内医药期刊报道的30例川芎嗪不良反应病例进行分类统计分析。结果:川芎嗪致不良反应与性别无关,多发生于>50a年龄组,其出现时间可发生于用药后的各个时间段。不良反应累及机体多个器官系统,临床表现复杂多样,主要表现为变态反应,严重者可出现过敏性休克。结论:临床医师、药师应了解川芎嗪所致不良反应的规律和特点,加强其应用的监测,以减少不良反应的发生。
OBJECTIVE： To explore the general pattern and characteristics of adverse drug reactions （ADRs） induced by Tetramcthylpyrazine（TMP） so as to provide references for clinical rational drug use. METHODS： A statistical analysis was conducted on 30 TMP induced ADR cases reported in domestic medical journals. RESULTS： ADRs of TMP were independent of patient＇ s sex, and which were more often seen in patients aged above 50. The ADRs could occur at any time after medication and involve multiple organs and systems. The clinical manifestations were various and manifested as allergic reaction or even allergic shock in severe cases. CONCLUSION： Doctors and pharmacists should master the pattern and characteristics of ADRs induced by TMP, and strengthen monitoring on the use of TMP to reduce the incidence of ADRs induced by TMP.
出处
《中国药房》
CAS
CSCD
北大核心
2008年第24期1908-1910,共3页
China Pharmacy
关键词
川芎嗪
不良反应
文献
分析
Tetramethylpyrazine（TMP）
ADR
Literature
Analysis
