摘要
诱发超排卵条件下进行16例配子输卵管内移植（GIFT），共发生5例卵巢过度刺激综合征（OHSS），OHSS及重度OHSS发生率分别为31．3％（5／16）及6．3％（1／16）。结果提示：OHSS的发生主要与hMG、hCG用量尤其是黄体期hCG用量有密切关系，注射hCG前血巳水平≥1500ng／L及卵泡数≥10个为发生OHSS的高危因素；妊娠可以促进或加重OHSS；通过连续阴道B超监测卵泡生长；调节hMG用量；结合注射hCG前血E2水平决定黄体期hCG用量，可有效地防止OHSS发生。
There were 5/16 patients with OHSS (4 mild to moderate cases and 1 severe case) in the cycles of induction of superovulation for GIFT procedures. The incidences of common OHSS and severe OHSS were 31. 3 % and 6.3%, respectively. No significant difference was found in age and etiology of infertility between the patients with and without OHSS (P>0.05). The dosages of hMG and hCG given in luteal phase for OHSS were signsificantly higher than for non OHSS (P<0.05). E2 level and number of follicles of these two groups were significantly different (P<0.05). The incidence of OHSS in pregnancy cycles was 5 fold than in nonpregnancy cycles (57% and 11%). Our result showed that the incidence of OHSS was closely associated with dosage of hMG/hCG. E2 level≥1 500 ng/L and number of follicles≥10 are the high risk factors of OHSS, and it is also more frequently seen in pregnant cycles. Carefully monitoring during hMG induction by transvaginal sonography and serum E2 assay can effectively prevent OHSS.
出处
《同济医科大学学报》
CSCD
1997年第5期391-393,396,共4页
Acta Universitatis Medicinae Tongji
基金
湖北省科委资助!No.90J57
关键词
卵巢过度刺激
综合征
排卵诱导
预测
防治
ovarian hyperstimulation syndrome
induction of superovulation
